Friday, July 10, 2026

Intelligence · Clinical pipeline

Autoimmune & immunology · Phase II

Autoimmune & immunology programs at Phase II — ClinicalTrials.gov pipeline intelligence.

Programs 325

Quick answer

Autoimmune & immunology Phase II programs: NovaPharmaNews indexes 325 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

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  1. VTX002-201

    Lacuna Pharma Pty Ltd

    Moderately to Severely Active Ulcerative Colitis

    phase 2 small molecule active

    1 trial
  2. VX-150

    Vertex Pharmaceuticals (Australia) Pty.

    Osteoarthritis

    phase 2 small molecule completed

    1 trial
  3. VX-702

    Vertex Pharmaceuticals (Australia) Pty.

    Rheumatoid Arthritis

    phase 2 small molecule completed

    2 trials
  4. VX-765

    Vertex Pharmaceuticals (Australia) Pty.

    Psoriasis

    phase 2 small molecule completed

    1 trial
  5. Vancomycin Pre-Treatment

    Seres Therapeutics

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial
  6. Vedolizumab 300 MG Injection [Entyvio]

    Takeda

    Immune Checkpoint Inhibitor-Related Colitis

    phase 2 small molecule active

    1 trial
  7. Vedolizumab intravenous injection

    Takeda

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial
  8. Veltuzumab

    Takeda

    Rheumatoid Arthritis

    phase 2 small molecule terminated

    1 trial
  9. Voclosporin High Dose

    Aurinia Pharmaceuticals

    Lupus Nephritis

    phase 2 small molecule completed

    1 trial
  10. WA42985

    Hoffmann-La Roche

    Lupus Nephritis (LN)

    phase 2 small molecule active

    1 trial
  11. Xanthohumol

    NORTHWEST BIOTHERAPEUTICS INC

    Crohn Disease

    phase 2 small molecule active

    1 trial
  12. ZASOCITINIB

    Takeda

    Moderate to Severely Active Ulcerative Colitis & Moderate to Severely Active Crohn's Disease

    phase 2 small molecule active

    1 trial
  13. ZB012-02-001

    Zenas BioPharma

    Systemic Lupus Erythematosus

    phase 2 small molecule active

    1 trial
  14. ZL-1102 1% w/w gel BID for 16 weeks

    Hong Kong Baptist University

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial
  15. Zanubrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Refractory/Relapsed Autoimmune Hemolytic Anemia

    phase 2 small molecule active

    1 trial
  16. Zasocitinib

    Takeda

    Crohn's Disease

    phase 2 small molecule active

    2 trials
  17. Zilretta

    Pacira Ireland Limited

    Osteoarthritis of Hip

    phase 2 small molecule terminated

    1 trial
  18. Zr89

    Disc Medicine

    giant cell arteritis, rheumatoid arthritis

    phase 2 small molecule active

    1 trial
  19. [68Ga]FAPI-46

    Disc Medicine

    giant cell arteritis - polymyalgia rheumatica spectrum disease

    phase 2 small molecule active

    1 trial
  20. amobarbital/Gel-One (one dose)

    United Therapeutics Europe Ltd

    Osteoarthritis

    phase 2 small molecule completed

    1 trial
  21. bimekizumab

    Lacuna Pharma Pty Ltd

    Moderate to Severe Plaque Psoriasis

    phase 2 small molecule active

    1 trial
  22. corticosteroids

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Severe Colitis (ASC)

    phase 2 small molecule active

    1 trial
  23. cyclophosphamide

    Ultragenyx UK Limited

    Anemia, Hemolytic, Autoimmune

    phase 2 small molecule completed

    1 trial
  24. cytarabine

    Ultragenyx UK Limited

    Lupus Erythematosus, Systemic

    phase 2 small molecule completed

    1 trial
  25. edratide

    Teva Pharma GmbH

    Systemic Lupus Erythematosus

    phase 2 small molecule terminated

    1 trial
  26. etiprednol dicloacetate

    Teva Pharma GmbH

    Crohn's Disease

    phase 2 small molecule completed

    1 trial
  27. glatiramer acetate

    Teva Pharma GmbH

    Crohns Disease

    phase 2 small molecule active

    1 trial
  28. honeybee venom (Apitoxin (Korea) Apitox (USA))

    Apimeds Pharmaceuticals US

    Osteoarthritis of the Knee

    phase 2 small molecule completed

    1 trial
  29. infloran

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Enterocolitis, Necrotizing

    phase 2 other terminated

    1 trial
  30. mesenchymal stem cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lupus Nephritis

    phase 2 mab active

    1 trial
  31. nicotinamide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cutaneous Lupus Erythematosus

    phase 2 small molecule active

    1 trial
  32. pectin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Crohn's Disease

    phase 2 small molecule terminated

    1 trial
  33. rituximab

    Chinese University of Hong Kong

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial
  34. sarilumab

    Sanofi-aventis Healthcare Pty Ltd

    Systemic Juvenile Idiopathic Arthritis (sJIA)

    phase 2 small molecule active

    1 trial
  35. tulisokibart, Placebo to MK-7240

    Merck Sharp and Dohme

    Psoriatic arthritis​​

    phase 2 small molecule active

    1 trial
  36. tulisokibart, Placebo to MK-7240 (tulisokibart)

    Merck Sharp and Dohme

    Rheumatoid Arthritis

    phase 2 small molecule active

    1 trial
  37. vilamakitug

    XBiotech Germany GmbH

    Axial Spondyloarthritis

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many autoimmune & immunology Phase II programs exist?

325 programs match both the therapeutic area and stage filters in our published index.