Autoimmune & immunology · Phase II

Top sponsors

• Takeda 26 programs
• Teva Pharma 13 programs
• Lakefront Biotherapeutics NV 12 programs
• Anaxis Pharma 11 programs
• Chinese Academy of 11 programs
• Novartis India 11 programs
• Sanofi-Aventis U.S 10 programs
• Pacira Ireland 9 programs
• United Therapeutics Europe 8 programs
• RIGEL PHARMACEUTICALS 6 programs
• Regeneron UK 6 programs
• Vertex Pharmaceuticals (Australia) 6 programs

1. Rilzabrutinib

   Sanofi-aventis Healthcare Pty Ltd

   Warm autoimmune hemolytic anemia

   phase 2 · small molecule · active

   1 trial →

2. Roflumilast

   Arcutis Biotherapeutics

   Plaque Psoriasis

   phase 2 · small molecule · completed

   1 trial →

3. Roflumilast Cream 0.3%

   Arcutis Biotherapeutics

   Plaque Psoriasis

   phase 2 · small molecule · completed

   1 trial →

4. Roflumilast foam 0.3%

   Arcutis Biotherapeutics

   Plaque Psoriasis

   phase 2 · small molecule · completed

   1 trial →

5. SAR441566

   Sanofi Pasteur

   Crohn's Disease

   phase 2 · small molecule · active

   1 trial →

6. SAR442970, NANOBODY® Placebo

   Sanofi-aventis Healthcare Pty Ltd

   Ulcerative Colitis

   phase 2 · small molecule · active

   1 trial →

7. SAR443122

   Sanofi Pasteur

   Colitis Ulcerative

   phase 2 · small molecule · active

   1 trial →

8. SCD-044-19-14

   Lacuna Pharma Pty Ltd

   moderate to severe plaque psoriasis

   phase 2 · small molecule · active

   1 trial →

9. SPD476-202

   Takeda

   Colitis, Ulcerative

   phase 2 · small molecule · completed

   1 trial →

10. SPI-62-CL-2003

    Lacuna Pharma Pty Ltd

    Polymyalgia rheumatica (PMR)

    phase 2 · small molecule · active

    1 trial →

11. SPY001

    Spyre Therapeutics

    Ulcerative Colitis

    phase 2 · small molecule · active

    1 trial →

12. SPY002-072

    Spyre Therapeutics

    Rheumatoid Arthritis

    phase 2 · small molecule · active

    1 trial →

13. SPY123-201

    Spyre Therapeutics

    Moderately to Severely Active Ulcerative Colitis

    phase 2 · small molecule · active

    1 trial →

14. SPYPBO-101 Placebo to SPY072, SPY072

    Spyre Therapeutics

    Moderately to Severely Active Rheumatologic Disease

    phase 2 · small molecule · active

    1 trial →

15. Sargramostim

    Hospital Authority, Hong Kong

    Pulmonary Alveolar Proteinosis, Autoimmune

    phase 2 · small molecule · completed

    1 trial →

16. Sarilumab

    Regeneron UK Limited

    Juvenile Idiopathic Arthritis

    phase 2 · small molecule · completed

    1 trial →

17. Sarilumab SAR153191 (REGN88)

    Regeneron UK Limited

    Juvenile Idiopathic Arthritis

    phase 2 · small molecule · active

    1 trial →

18. Sonelokimab

    MoonLake Immunotherapeutics

    axial spondyloarthritis

    phase 2 · small molecule · active

    1 trial →

19. Spesolimab

    Boehringer Ingelheim

    Generalized Pustular Psoriasis

    phase 2 · small molecule · active

    1 trial →

20. Splinting

    United Therapeutics Europe Ltd

    Hand Osteoarthritis

    phase 2 · other · completed

    1 trial →

21. Stem cells

    Takeda

    Rheumatoid Arthritis Aggravated

    phase 2 · gene therapy · completed

    1 trial →

22. Stromal-vascular fraction

    Century Therapeutics

    Knee Osteoarthritis

    phase 2 · mab · active

    1 trial →

23. SynAct-CS010

    Lacuna Pharma Pty Ltd

    Polymyalgia rheumatica

    phase 2 · small molecule · active

    1 trial →

24. TAK-018

    Takeda

    Crohn Disease

    phase 2 · small molecule · terminated

    1 trial →

25. TAK-079

    Takeda

    Myasthenia Gravis

    phase 2 · small molecule · completed

    1 trial →

26. TAK-279

    Takeda

    Ulcerative Colitis

    phase 2 · small molecule · active

    1 trial →

27. TAK-279

    Takeda

    Crohn's Disease

    phase 2 · small molecule · active

    1 trial →

28. TAK-279-CD-2001

    Takeda

    Moderately to Severely Active Crohn's Disease

    phase 2 · small molecule · active

    1 trial →

29. TAK-279-UC-2001

    Takeda

    Moderate to Severely Active Ulcerative Colitis

    phase 2 · small molecule · active

    1 trial →

30. TAK-715 and methotrexate

    Takeda

    Arthritis, Rheumatoid

    phase 2 · small molecule · completed

    1 trial →

31. TAK-783 and methotrexate

    Takeda

    Arthritis, Rheumatoid

    phase 2 · small molecule · completed

    1 trial →

32. TEV-48574

    Lacuna Pharma Pty Ltd

    Crohn’s disease, Ulcerative colitis

    phase 2 · small molecule · active

    1 trial →

33. TEV-48574

    Teva Pharma GmbH

    Crohn Disease

    phase 2 · small molecule · completed

    1 trial →

34. TEV-48574 Dose Regimen A

    Teva Pharma GmbH

    Crohn Disease

    phase 2 · small molecule · active

    1 trial →

35. TV-45070

    Teva Pharma GmbH

    Osteoarthritis of the Knee

    phase 2 · small molecule · completed

    1 trial →

36. TV48574-IMM-20036

    Lacuna Pharma Pty Ltd

    Crohn’s disease, Ulcerative colitis

    phase 2 · small molecule · active

    1 trial →

37. Taodan Granules

    Universal Integrated

    Psoriasis Vulgaris

    phase 2 · small molecule · active

    1 trial →

38. Teduglutide (ALX-0600)

    Takeda

    Crohn's Disease

    phase 2 · small molecule · completed

    1 trial →

39. Telitacicept

    The First People's Hospital of Lianyungang

    Systemic Lupus Erythematosus

    phase 2 · small molecule · active

    1 trial →

40. Telotristat Etiprate

    LEXICON PHARMACEUTICALS, INC.

    Ulcerative Colitis

    phase 2 · small molecule · completed

    1 trial →

41. Tocilizumab Injectable Product

    Tang-Du Hospital

    Myasthenia Gravis, Generalized

    phase 2 · small molecule · active

    1 trial →

42. Topical Rose Bengal, 0.005%

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 · small molecule · completed

    1 trial →

43. Triamcinolone Acetonide Acetate and Urea Cream.

    Universal Integrated

    Psoriasis Vulgaris

    phase 2 · small molecule · active

    1 trial →

44. Tyenne 162 mg solution for injection in pre-filled pen

    Cardiff Oncology

    Psoriatic Arthritis, Rheumatoid Arthritis

    phase 2 · small molecule · active

    1 trial →

45. Tyenne 162 mg solution for injection in pre-filled pen

    Cardiff Oncology

    Psoriatic Arthritis, Rheumatoid Arthritis

    phase 2 · small molecule · active

    1 trial →

46. Ublituximab

    TG THERAPEUTICS, INC.

    Autoimmune Disorders

    phase 2 · small molecule · active

    1 trial →

47. Upadacitinib, Upadacitinib

    AbbVie Deutschland GmbH & Co. KG

    Crohn's Disease (CD)

    phase 2 · small molecule · active

    1 trial →

48. Uplizna 100 mg concentrate for solution for infusion

    Amgen

    Generalized Myasthenia Gravis

    phase 2 · small molecule · active

    1 trial →

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