Autoimmune & immunology · Phase II

Top sponsors

• Takeda 26 programs
• Teva Pharma 13 programs
• Lakefront Biotherapeutics NV 12 programs
• Anaxis Pharma 11 programs
• Chinese Academy of 11 programs
• Novartis India 11 programs
• Sanofi-Aventis U.S 10 programs
• Pacira Ireland 9 programs
• United Therapeutics Europe 8 programs
• RIGEL PHARMACEUTICALS 6 programs
• Regeneron UK 6 programs
• Vertex Pharmaceuticals (Australia) 6 programs

1. Descartes-08

   Cartesian Therapeutics

   Systemic Lupus Erythematosus (SLE)

   phase 2 · small molecule · active

   1 trial →

2. Descartes-08

   Cartesian Therapeutics

   Myasthenia Gravis, Generalized

   phase 2 · small molecule · active

   1 trial →

3. Descartes-08

   Cartesian Therapeutics

   Childhood-onset Systemic Lupus Erythematous

   phase 2 · small molecule · active

   1 trial →

4. Dex 21-P

   Quince Therapeutics

   Ulcerative Colitis

   phase 2 · small molecule · completed

   1 trial →

5. Diamyd

   Wuhan Createrna Science and Technology Co., Ltd

   Latent Autoimmune Diabetes in Adults (LADA)

   phase 2 · small molecule · active

   1 trial →

6. Double-Blind 0.2mg CBP-307

   S.L

   Moderate to Severe Ulcerative Colitis

   phase 2 · small molecule · completed

   1 trial →

7. Duobrii

   Bausch & Lomb Incorporated

   Plaque Psoriasis

   phase 2 · small molecule · active

   1 trial →

8. Dupilumab

   Regeneron UK Limited

   Colitis Ulcerative

   phase 2 · small molecule · active

   1 trial →

9. EP-104IAR 25 mg

   EUPRAXIA PHARMACEUTICALS INC.

   Osteoarthritis, Knee

   phase 2 · small molecule · completed

   1 trial →

10. Efavaleukin alfa

    Amgen

    Ulcerative Colitis

    phase 2 · small molecule · terminated

    1 trial →

11. Elsubrutinib

    AbbVie

    Systemic Lupus Erythematosus (SLE)

    phase 2 · small molecule · completed

    1 trial →

12. Eltrekibart

    Eli Lilly and Company

    Ulcerative Colitis

    phase 2 · small molecule · active

    1 trial →

13. Enekinragene Inzadenovec (PCRX-201)

    Pacira Ireland Limited

    Osteoarthritis (OA) of the Knee

    phase 2 · mab · active

    1 trial →

14. Enpatoran Placebo, Enpatoran

    Merck Sharp and Dohme

    Systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE)

    phase 2 · small molecule · active

    1 trial →

15. Enpatoran low dose

    Serono Europe Limited

    Systemic Lupus Erythematosus

    phase 2 · small molecule · completed

    1 trial →

16. Entyvio 300 mg powder for concentrate for solution for infusion

    Takeda

    Ulcerative Colitis or Crohn's Disease

    phase 2 · small molecule · active

    1 trial →

17. Etanercept

    United Therapeutics Europe Ltd

    Lupus Erythematosus, Discoid

    phase 2 · small molecule · completed

    1 trial →

18. Etrasimod

    Arena Pharmaceutical Enterprises Limited

    Ulcerative Colitis

    phase 2 · small molecule · completed

    1 trial →

19. FT819

    Zafatek

    Lupus Nephritis

    phase 2 · mab · active

    1 trial →

20. FX005

    Pacira Ireland Limited

    Osteoarthritis, Knee

    phase 2 · small molecule · completed

    1 trial →

21. FX006

    Pacira Ireland Limited

    Osteoarthritis of the Shoulder

    phase 2 · small molecule · terminated

    1 trial →

22. FX006 10 mg

    Pacira Ireland Limited

    Osteoarthritis of the Knee

    phase 2 · small molecule · completed

    2 trials →

23. FX006 32 mg

    Pacira Ireland Limited

    Osteoarthritis, Hip

    phase 2 · small molecule · completed

    1 trial →

24. FX006 32 mg

    Pacira Ireland Limited

    Bilateral Knee Osteoarthritis

    phase 2 · small molecule · completed

    1 trial →

25. FX006 32 mg

    Pacira Ireland Limited

    Post-traumatic Osteoarthritis of the Knee

    phase 2 · small molecule · terminated

    1 trial →

26. FX006 32 mg

    Pacira Ireland Limited

    Osteoarthritis of the Shoulder

    phase 2 · small molecule · completed

    1 trial →

27. Filgotinib

    Lakefront Biotherapeutics NV

    Small Bowel Crohn's Disease

    phase 2 · small molecule · completed

    1 trial →

28. Filgotinib

    Lakefront Biotherapeutics NV

    Fistulizing Crohn's Disease

    phase 2 · small molecule · completed

    1 trial →

29. Fostamatinib

    AstraZeneca

    Rheumatoid Arthritis

    phase 2 · small molecule · terminated

    1 trial →

30. Fostamatinib 150 mg bid

    RIGEL PHARMACEUTICALS INC

    Warm Antibody Autoimmune Hemolytic Anemia

    phase 2 · small molecule · completed

    1 trial →

31. Fostamatinib Disodium (R935788)

    RIGEL PHARMACEUTICALS INC

    Systemic Lupus Erythematosus

    phase 2 · small molecule · terminated

    1 trial →

32. Fostamatinib disodium (R935788)

    RIGEL PHARMACEUTICALS INC

    Rheumatoid Arthritis

    phase 2 · small molecule · completed

    2 trials →

33. Frexalimab, Matched Placebo for Test

    Sanofi-aventis Healthcare Pty Ltd

    Systemic lupus erythematosus

    phase 2 · small molecule · active

    1 trial →

34. GLPG0259 oral capsule

    Lakefront Biotherapeutics NV

    Rheumatoid Arthritis

    phase 2 · small molecule · completed

    1 trial →

35. GLPG0634

    Lakefront Biotherapeutics NV

    Rheumatoid Arthritis

    phase 2 · small molecule · completed

    4 trials →

36. GLPG0634

    Lakefront Biotherapeutics NV

    Crohn's Disease

    phase 2 · small molecule · completed

    1 trial →

37. GLPG0974

    Lakefront Biotherapeutics NV

    Ulcerative Colitis

    phase 2 · small molecule · completed

    1 trial →

38. GLPG1205

    Lakefront Biotherapeutics NV

    Ulcerative Colitis

    phase 2 · small molecule · completed

    1 trial →

39. GLPG1972

    Lakefront Biotherapeutics NV

    Osteoarthritis

    phase 2 · small molecule · completed

    1 trial →

40. GLPG3667

    Lakefront Biotherapeutics NV

    Systemic Lupus Erythematosus

    phase 2 · small molecule · completed

    1 trial →

41. GLPG3970

    Lakefront Biotherapeutics NV

    Ulcerative Colitis

    phase 2 · small molecule · completed

    1 trial →

42. GLPG3970

    Lakefront Biotherapeutics NV

    Rheumatoid Arthritis

    phase 2 · small molecule · completed

    1 trial →

43. GR-MD-02

    GALECTIN THERAPEUTICS INC

    Psoriasis

    phase 2 · small molecule · completed

    1 trial →

44. GS-US-409-5704

    Gilead Sciences Pty Limited

    Ulcerative Colitis (UC)

    phase 2 · small molecule · active

    1 trial →

45. GSK3196165 Dose 1

    GlaxoSmithKline

    Arthritis, Rheumatoid

    phase 2 · small molecule · completed

    1 trial →

46. Glutamine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatic Heart Disease

    phase 2 · small molecule · completed

    1 trial →

47. Guselkumab

    Janssen Cilag International NV

    Colitis, Ulcerative

    phase 2 · mab · active

    1 trial →

48. HZNP-DAX-202

    Elan Pharma International

    Primary Discoid Lupus Erythematosus

    phase 2 · small molecule · active

    1 trial →

Frequently asked questions