Wednesday, July 8, 2026

Patent intelligence · US

US 12263225

Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of use thereof to targe…

granted A61KA61K2039/505A61K31/713A61K47/10
Status granted
Linked drugs 1
Pipeline programs 6
Years to expiry 19
Applicant portfolio 82
Patent details — US 12263225
Jurisdiction
US
Status
granted
Grant date
Apr 1, 2025
Expiration
Mar 27, 2045
Claims
30
CPC classes
A61K, A61K2039/505, A61K31/713, A61K47/10
View on Google Patents ↗

Quick answer

US 12263225 (Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of use thereof to target dystrophin and to treat Duchenne muscular dystrophy) is held by Dyne Therapeutics, Inc.. Status: granted. Granted Apr 1, 2025. Expires Mar 27, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
30
CPC classes
A61K, A61K2039/505, A61K31/713, A61K47/10, A61K47/549, A61K47/6807

More from Dyne Therapeutics, Inc.

Related pharmaceutical patents in our USPTO index.

  1. US 12428487

    Complexes comprising an anti-transferrin receptor antibody linked to an oligonicleotide and method of delivering oligonucleotide to a subject

    Dyne Therapeutics, Inc. · Expires Sep 25, 2045

    granted
  2. US 12403203

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Expires Aug 28, 2045

    granted
  3. US 12397062

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Expires Aug 21, 2045

    granted
  4. US 12370264

    Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject

    Dyne Therapeutics, Inc. · Expires Jul 24, 2045

    granted
  5. US 12357703

    Muscle-targeting complexes comprising an anti-transferin receptor antibody linked to an oligonucleotide and method of use thereof to induce exon skipping

    Dyne Therapeutics, Inc. · Expires Jul 10, 2045

    granted
  6. US 12329824

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Expires Jun 12, 2045

    granted
  7. US 12329825

    Muscle targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of use thereof to induce exon skipping of exon 44 of dystrophin in a subject

    Dyne Therapeutics, Inc. · Expires Jun 12, 2045

    granted
  8. US 12325753

    Method of using an anti-transferrin receptor antibody to deliver an oligonucleotide to a subject having facioscapulohumeral muscular dystrophy

    Dyne Therapeutics, Inc. · Expires Jun 5, 2045

    granted

Frequently asked questions

What is US patent 12263225?

US 12263225 (Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of use thereof to target dystrophin and to treat Duchenne muscular dystrophy) is held by Dyne Therapeutics, Inc.. Status: granted. Granted Apr 1, 2025. Expires Mar 27, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 12263225?

Dyne Therapeutics, Inc. is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 82 pharmaceutical patents for this assignee.

When does US 12263225 expire?

Our index shows an expiration date of Mar 27, 2045 (19 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.