Wednesday, July 8, 2026

Patent intelligence · US

US 12357703

Muscle-targeting complexes comprising an anti-transferin receptor antibody linked to an oligonucleotide and method of use thereof to induce …

granted A61KA61K2039/505A61K31/713A61K47/10
Status granted
Linked drugs 1
Pipeline programs 6
Years to expiry 19
Applicant portfolio 82
Patent details — US 12357703
Jurisdiction
US
Status
granted
Grant date
Jul 15, 2025
Expiration
Jul 10, 2045
Claims
30
CPC classes
A61K, A61K2039/505, A61K31/713, A61K47/10
View on Google Patents ↗

Quick answer

US 12357703 (Muscle-targeting complexes comprising an anti-transferin receptor antibody linked to an oligonucleotide and method of use thereof to induce exon skipping) is held by Dyne Therapeutics, Inc.. Status: granted. Granted Jul 15, 2025. Expires Jul 10, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
30
CPC classes
A61K, A61K2039/505, A61K31/713, A61K47/10, A61K47/549, A61K47/6807

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Frequently asked questions

What is US patent 12357703?

US 12357703 (Muscle-targeting complexes comprising an anti-transferin receptor antibody linked to an oligonucleotide and method of use thereof to induce exon skipping) is held by Dyne Therapeutics, Inc.. Status: granted. Granted Jul 15, 2025. Expires Jul 10, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 12357703?

Dyne Therapeutics, Inc. is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 82 pharmaceutical patents for this assignee.

When does US 12357703 expire?

Our index shows an expiration date of Jul 10, 2045 (19 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.