Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11786589

    Human rotavirus strains and vaccines

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11786605

    Site specific antibody-drug conjugates with peptide-containing linkers

    Mersana Therapeutics, Inc. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11786536

    Salts of potassium ATP channel openers and uses thereof

    ESSENTIALIS, INC. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11786553

    Chimeric cytokine receptors bearing a PD-1 ectodomain

    Allogene Therapeutics, Inc. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11786464

    PH responsive block copolymer compositions and micelles that inhibit MCT 1 and related proteins

    The Board of Regents of the University of Texas System · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11790574

    System and method for carbon dioxide angiographic roadmap imaging

    GE Precision Healthcare LLC · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11788141

    MVD as epigenetic marker for the identification of immune cells, in particular CD56+ NK cells

    Precision for Medicine GmbH · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11787840

    Compositions and methods for treating and preventing autoimmune induced cardiac long QT syndrome

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11788077

    Polynucleotides encoding optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome

    Precision BioSciences, Inc. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11787869

    Methods of using muscle targeting complexes to deliver an oligonucleotide to a subject having facioscapulohumeral muscular dystrophy or a disease associated with muscle weakness

    Dyne Therapeutics, Inc. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11787867

    Anti-GITR antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 17 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. CA 3255134

    COMPOSITION D'ALLERGÈNE D'ARACHIDE

    ALK ABELLO AS [DK] · Granted Thu Oct 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11793812

    Methods of treating endometriosis

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11793780

    Prodrugs of treprosiinil

    United Therapeutics Corporation · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11793815

    Oxindoles and methods of use thereof

    Aligos Therapeutics, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11793806

    Pyruvate kinase activators for use in therapy

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11793855

    TFPI inhibitors and methods of use

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11793871

    Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11793825

    Biomarkers for predicting responsiveness to decitabine therapy

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11793870

    Live attenuated strains of foot and mouth disease modified by deoptimization and uses thereof

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11795443

    Uses of adenosine base editors

    Beam Therapeutics Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11795192

    Antimicrobial compounds, compositions, and uses thereof

    Lakewood Amedex, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11795130

    Process for separating a constituent/cannabinoid using a chromatographic resin

    KAZMIRA LLC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11793912

    Cross-linked fatty acid-based biomaterials

    ATRIUM MEDICAL CORPORATION · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11795156

    Bicyclic carboxamides and methods of use thereof

    TEMPEST THERAPEUTICS, INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11795216

    Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11795232

    Engineered transferrin receptor binding polypeptides

    DENALI THERAPEUTICS INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11795233

    Muscle-targeting complex comprising an anti-transferrin receptor antibody linked to an oligonucleotide

    Dyne Therapeutics, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11795234

    Methods of producing muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide

    Dyne Therapeutics, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11795457

    Compositions and methods for treatment of Friedreich's Ataxia

    The Board of Regents of the University of Texas System · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11795235

    Immunotoxins with albumin binding domain

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11793860

    Vault complexes for cytokine delivery

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11793772

    Pharmaceutical composition comprising THA as active ingredient for treating breast cancer

    KOREA UNITED PHARM. INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11795176

    Solid forms of Alpha-1062 gluconate

    ALPHA COGNITION INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11793776

    Methods of administering solriamfetol to lactating women

    AXSOME MALTA LTD. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11793888

    Methods and compositions for engineering immunity

    Sangamo Therapeutics, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11793810

    Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11793177

    Animal model of Angelman Syndrome

    The Regents of the University of California · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11793796

    Inhibition of crystal growth of roflumilast

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11793819

    Natural combination hormone replacement formulations and therapies

    Compass Therapeutics LLC · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11793777

    Methods and compositions for treating conditions associated with an abnormal inflammatory response

    First Wave Bio, Inc. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11793816

    Methods for enhancing cytotoxic cancer therapy through inhibition of ATG4B

    Northwestern University · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11795180

    Formulation of a pan-JAK inhibitor

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11795215

    Anti-mesothelin chimeric antigen receptor specifically binding to mesothelin

    CELLENGENE INC. · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11795434

    Engineered stem cells and cellular products produced and secreted by such cells, methods of preparing, and uses thereof

    L'Institut de Cardiologie de Montréal · Granted Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. CA 3249631

    PROCÉDÉS ET COMPOSITIONS POUR RALENTIR LE DÉVELOPPEMENT DU DIABÈTE OU RÉDUIRE UN RISQUE DE DIABÈTE

    ABBOTT LAB · Granted Thu Oct 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11801241

    Muscarinic M2 receptor blockade to delay or prevent onset of progressive memory decline

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11802158

    Bispecific anti-CD3 antibodies, bispecific activatable anti-CD3 antibodies, and methods of using the same

    CytomX Therapeutics, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.