Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11730820

    Peptidic blocks for nucleic acid delivery

    S. M. DISCOVERY GROUP INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11732037

    Weight loss regimen

    Boards of Regents, The University of Texas System · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11732024

    VEGF antagonist formulations suitable for intravitreal administration

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11732007

    Therapeutic compounds and methods

    The Regents of the University of California · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11732005

    Peptidomimetic proteasome inhibitors

    Tri-Institutional Therapeutics Discovery Institute, Inc. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11730828

    Gene therapy for haploinsufficiency

    The Regents of the University of California · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11731986

    Inhibitors of low molecular weight protein tyrosine phosphatase (LMPTP) and uses thereof

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11731953

    Methods and compounds for restoring mutant p53 function

    PMV PHARMACEUTICALS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11731966

    Compounds and their methods of use

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11731978

    3-(ethoxydifluoromethyl)-6-(5-fluoro-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-[1,2,4]triazolo[4,3-a]pyridine as an ion channel modulator

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11732025

    Anti-VEGF protein compositions and methods for producing the same

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11732259

    Peptide oligonucleotide conjugates

    Sarepta Therapeutics, Inc. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. WO 2023159093

    COMPOSITIONS NUTRITIONNELLES COMPRENANT DES OLIGOSACCHARIDES DE LAIT MATERNEL ET DE L'IMMUNOGLOBULINE BOVINE

    ABBOTT LAB [US] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. WO 2023156493

    FORMES CRISTALLINES DE NALTREXONE

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. WO 2023158844

    COMPOSITIONS NUTRITIONNELLES EN POUDRE TRAITÉES THERMIQUEMENT ET PROCÉDÉS DE MAINTIEN DE (2S)-HESPÉRIDINE

    ABBOTT LAB [US] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11737979

    Method of making lipid-encapsulated RNA nanoparticles

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11737983

    Storage stable sincalide formulations

    MAIA PHARMACEUTICALS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11739068

    Polymorphs of N-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazole-4-carboxamide and salts thereof

    KalVista Pharmaceuticals Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11738085

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11739294

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11739137

    Single domain antibodies to SARS-CoV-2 nucleocapsid protein

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11739345

    Methods of treating phenylketonuria

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11739309

    CRISPR-Cas12J effector polypeptides and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11739162

    Side chain modified peptoids useful as structure-stabilizing coatings for biomaterials

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11737993

    Multiple myeloma treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11738009

    Bicyclic compounds and their use in the treatment of cancer

    TEMPEST THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11737991

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    TONIX PHARMA LIMITED · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11738019

    Substituted heterocycles as antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11739101

    Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof

    NURIX THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11739123

    Process for the preparation of cyclic depsipeptides

    OnKure, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11739297

    Method of increasing tumor killing activity of macrophages or monocytes comprising chimeric antigen receptor

    Carisma Therapeutics Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11739152

    Antibodies which bind Fc receptors (FcRn)

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11739074

    Ras inhibitors

    Revolution Medicines, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11738070

    Methods and compositions for improved cognition

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11738015

    Pharmaceutical compositions and methods of using the same

    NODEN PHARMA DESIGNATED ACTIVITY COMPANY · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11737981

    Cellulosic polymer nanoparticles and methods of forming them

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11738022

    Methods for inducing pupil dilation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11739121

    EPHA2 agonists and uses thereof

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11738050

    Compounds binding to fibroblast activation protein alpha

    Regents of the University of Minnesota · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11738038

    Highly active compounds against COVID-19

    Atea Pharmaceuticals, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11739132

    Separation moieties and methods of use thereof

    Werewolf Therapeutics, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11739133

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11739093

    Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors

    Revolution Medicines, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11738119

    Antimicrobial catheters

    The Board of Regents of the University of Texas System · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11738116

    Expanded nanofiber structures comprising electrospun nanofibers and a plurality of holes and methods of making and use thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11739063

    DREADD actuators

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11738053

    Methods and compositions for treating chronic granulomatous disease

    The Board of Regents of the University of Texas System · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11739086

    Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same

    Aclaris Therapeutics, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.