Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. KR 20230116805

    가도테리돌 제조를 위한 제조 방법

    BRACCO IMAGING SPA [IT] · Granted Fri Aug 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11718665

    Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins

    Rani Therapeutics, LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11717480

    Extracellular vesicles and methods and uses thereof

    The Regents of the University of California · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11718647

    Virus-like particles and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11717576

    Antibody-immune agonist conjugate and applications thereof

    GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11718616

    JAK kinase inhibitor compounds for treatment of respiratory disease

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11718655

    Masked interleukin-12 polypeptides

    Xilio Development, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11718613

    N-(phenylsulfonyl)benzamides and related compounds as Bcl-2 inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11718621

    Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use

    SPERO THERAPEUTICS, INC. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11718658

    T cell receptors that bind to mixed lineage leukemia (MLL)-specific phosphopeptides and methods of use thereof

    MiNK Therapeutics, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11717547

    Compositions and methods for the treatment of autosomal recessive congenital ichthyosis

    Krystal Biotech, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11717573

    Methods and compositions for the treatment of cancer

    SOUTH DAKOTA BOARD OF REGENTS · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11718612

    Inhibitors of receptor interacting protein kinase I for the treatment of disease

    The Board of Regents of the University of Texas System · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11718679

    CD137 antibodies and PD-1 antagonists and uses thereof

    Compass Therapeutics LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11718610

    Compounds containing benzosultam

    Medshine Discovery Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11718834

    Compositions and methods for producing recombinant AAV

    Sangamo Therapeutics, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11718852

    Non-liposomal systems for nucleic acid delivery

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11718591

    Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2- methylpentanoic acid and uses thereof

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11718589

    Compositions and methods of modulating short-chain dehydrogenase

    The Board of Regents of the University of Texas System · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11718576

    Compositions and methods comprising resveratrol

    Biocogent, LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11718530

    Allotrope of carbon having increased electron delocalization

    Structured Nano Carbon LLC · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11718596

    Amyloid targeting agents and methods of using the same

    The Regents of the University of California · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11717558

    Nucleic acid molecules encoding activin receptor type IIA variants

    Keros Therapeutics, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11717542

    Using tumor-navigating Salmonella to modulate tumor metabolism

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11717565

    Recombinant BCG overexpressing phoP-phoR

    LTD. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11718618

    Substituted pyrido[2,1-a]isoquinolines as VMAT2 inhibitors

    Neurocrine Biosciences, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11718641

    Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11717553

    Combined plant extract for getting rid of mites and acne and preparation method and use thereof

    Nanjing Institute for Comprehensive Utilization of Wild Plants, All China Federation of Supply and Marketing Corporation · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11718630

    Compositions and methods for treating cancer

    The Regents of the University of California · Granted Tue Aug 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. CA 3235923

    PROCEDES DE SYNTHESE A GRANDE ECHELLE DE COMPLEXES DE RADIONUCLEIDES

    ADVANCED ACCELERATOR APPLICATIONS [FR] · Granted Thu Aug 10 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 05 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11723949

    Modulators of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11723952

    Methods and compositions for treating Huntington's Disease

    Sangamo Therapeutics, Inc. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11723982

    Methods of treating an ocular disease or disorder

    The Regents of the University of California · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11723992

    Method for extraction and purification of 68GA

    The Board of Regents of the University of Texas System · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11725248

    Evaluation of mantle cell lymphoma and methods related thereto

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11725024

    Antibody drug conjugates

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11725209

    TMPRSS6 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11725208

    Conjugated antisense compounds and their use

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11723881

    Fortified CBD oil for treatment of PTSD

    Bright Green Corporation · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11723961

    Maspin, maspin derivatives, and maspin mimetics for reducing ROS, inflammation, and skin aging

    Northwestern University · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11723873

    Oral dosage form of ticagrelor and preparation method thereof

    Elite Pharmaceutical Solution Inc. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11723903

    Treatment of schizophrenia

    VANDA PHARMACEUTICALS INC. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11723362

    Broad-spectrum synergistic antimicrobial compositions

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11723864

    Antimicrobial and anti-inflammatory compositions

    The Board of Regents of the University of Texas System · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11723929

    Methods of improving cell-based therapy

    The Regents of the University of California · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11725008

    Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases

    The Board of Regents of the University of Texas System · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11723762

    LIDAR based 3-D imaging with far-field illumination overlap

    VELODYNE LIDAR, INC. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11723885

    Methods and compositions for interfering with extraction or conversion of a drug susceptible to abuse

    Acurx Pharmaceuticals, Inc. · Granted Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.