Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11638708

    Method of treatment of aggression

    Supernus Pharmaceuticals, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11639504

    Methods and compositions for regulation of transgene expression

    Sangamo Therapeutics, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11638706

    Methods for treating Huntington's disease

    PTC THERAPEUTICS, INC. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11639347

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11639359

    Bryoid compositions, methods of making and use thereof

    Aphios Corporation · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11638690

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11638747

    WT1 vaccine

    Inovio Pharmaceuticals, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11638753

    Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy

    PDS Biotechnology Corporation · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. WO 2023076144

    MÉTHODES ET COMPOSITIONS DESTINÉES À AMÉLIORER LA PRODUCTION ET LA SÉCRÉTION D'INSULINE

    ABBOTT LAB [US] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. WO 2023077094

    TRAITEMENT D'UN TROUBLE DÉPRESSIF MAJEUR

    ABBVIE INC [US] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. CA 3234495

    POLYTHERAPIE DE COMPLEXE DE RADIONUCLEIDES

    NOVARTIS AG [CH] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11642398

    Factor IX polypeptide formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11643656

    Antisense therapies for treating cancer

    The United States Government represented by the Department of Veterans Affairs · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11642319

    Targeted nanogels for urinary bladder therapies

    The Regents of the University of Colorado · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11643394

    Krüppel-like factor 15 (KLF15) small molecule agonists in kidney disease

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11642849

    In vivo live 3D printing of regenerative bone healing scaffolds for rapid fracture healing

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11642375

    Intracellular genomic transplant and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11643640

    Rift valley fever vaccine

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11642390

    Method of treatment with a fusion protein comprising apelin and an anti-APLNR antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11643446

    Progranulin variants

    DENALI THERAPEUTICS INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11642366

    Methods for preventing a serious health consequence and/or tissue damage after exposure to ionizing radiation and/or chemotherapy

    GLYCOMIRA THERAPEUTICS, INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11643453

    Cell

    AUTOLUS LIMITED · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11642401

    Activation of resident memory T cells for cancer immunotherapy

    Regents of the University of Minnesota · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11642374

    Intracellular genomic transplant and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11642379

    Hematopoietic stem cell engraftment

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11642364

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11642410

    Targeting microbubbles

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11642332

    (2R,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid

    Theravance Biopharma R&D IP, LLC · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11642335

    Chemical synthesis of clopidogrel active metabolites and disulfide conjugate prodrugs

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11643438

    Antimicrobial peptides and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11643388

    Inhibitors of alpha 2 beta 1 integrin and methods of use thereof

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11642323

    Method for modulating metabolism

    Brightseed, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11642419

    Compositions and methods for treating cardiovascular related disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11642384

    Compositions and methods for the treatment of Netherton Syndrome

    Krystal Biotech, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11642354

    Methods and compositions comprising ursolic acid and/or resveratrol for treating diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11642331

    Glucocorticoid receptor modulators to treat pancreatic cancer

    Corcept Therapeutics Incorporated · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11642023

    Hyperspectral imaging for detection of transmissible spongiform encephalopathy

    Regents of the University of Minnesota · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11642339

    Methods of treating symptoms of gastroparesis using velusetrag

    Theravance Biopharma R&D IP, LLC · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11648232

    Methods and compositions for treating excessive sleepiness

    AXSOME MALTA LTD. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11649251

    Substituted inhibitors of menin-MLL and methods of use

    Kura Oncology, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11648210

    Compositions and methods for organ specific delivery of nucleic acids

    The Board of Regents of the University of Texas System · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11648237

    5HT agonists for treating disorders

    The Regents of the University of California · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11649468

    Targeted integration into the PPP1R12C locus

    Sangamo Therapeutics, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11648274

    Polypeptide

    AUTOLUS LIMITED · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11649261

    Crystalline forms of a CD73 inhibitor and uses thereof

    Arcus Biosciences, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11648267

    Methods and compositions for gene inactivation

    Sangamo Therapeutics, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11649230

    Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof

    VTV THERAPEUTICS LLC · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11649459

    Superoxide dismutase 1 (SOD1) iRNA compositions and methods of use thereof for treating or preventing superoxide dismutase 1-(SOD1-) associated neurodegenerative diseases

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.