Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10524458

    Humanized C3 animals

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10525053

    Abuse-deterrent pharmaceutical compositions of opioids and other drugs

    Collegium Pharmaceutical, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10525120

    Methods and compositions for live attenuated viruses

    Takeda Vaccines, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10525106

    Angiopoietin-based interventions for treating cerebral malaria

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10525051

    Compositions and methods for achieving sustained therapeutic drug concentrations in a subject

    Nektar Therapeutics · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10526359

    Thiosaccharide mucolytic agents

    The Regents of the University of California · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10526346

    Histone deacetylase inhibitors

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10526294

    Pyrrolobenzodiazepines and conjugates thereof

    Mersana Therapeutics, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10525068

    Anti-inflammatory properties of marine lipid compositions

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10525248

    Apparatus and method for promoting fluid uptake into an implant

    Nano Precision Medical, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10526656

    Methods of diagnosing chronic obstructive pulmonary disease (COPD) using novel molecular biomarkers

    Transgenion—International Institute for Regenerative Translational Medicine GmbH · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10526655

    Methods for evaluating COPD status

    Veracyte, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10526295

    Nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10526330

    JAK kinase inhibitor compounds for treatment of respiratory disease

    Theravance Biopharma R&D IP, LLC · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10525104

    Predictive and prognostic biomarkers related to anti-angiogenic therapy of metastatic colorectal cancer

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10526604

    Modulation of nuclear-retained RNA

    Ionis Pharmaceuticals, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10525086

    Methods for growth and maturation of ovarian follicles

    Northwestern University · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10526373

    Peptide showing melanin generation-promoting activity and use thereof

    CAREGEN CO., LTD. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10525123

    Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10526297

    Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases

    United Kingdom Research and Innovation · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10526397

    Non-immunogenic single domain antibodies

    Inhibrx, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10525101

    Methods of treating inflammatory or autoimmune disorders with compounds that bind macrophage migration inhibitory factor

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10526370

    Pentapeptide associated with integrin receptor alpha vbeta3

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10525126

    Modified lipopolysaccharide glycoform and method of use

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10526400

    Humanized pertussis antibodies and used thereof

    The Board of Regents of the University of Texas System · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10526619

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10526403

    Anti-activin A antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10526285

    Therapeutic compounds and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10526414

    Use of anti-semaphorin-4D antibodies in combination with an immune modulating therapy to inhibit tumor growth and metastases

    VACCINEX, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10526344

    Amino acid acylation reagents and methods of using the same

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10526576

    Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells

    REGENERATIVE MEDICAL SOLUTIONS, INC. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10525046

    Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases

    ACADIA Pharmaceuticals Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10525090

    Compositions and methods for the treatment of autosomal recessive congenital ichthyosis

    Krystal Biotech, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10525290

    Compositions for forming films having a desired degree of obscuration and methods of making and using the same

    W.R. Grace & Co.-Conn. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10525052

    Abuse-deterrent drug formulations

    Collegium Pharmaceutical, Inc. · Granted Tue Jan 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. CA 3105778

    POLYTHERAPIE AVEC DES ANTAGONISTES DU CGRP ET DES DERIVES DE CLOSTRIDIUM

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jan 09 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 04 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10532101

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10531654

    Methods and compositions for vein harvest and autografting

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10532022

    Whole stablized olive mill process water, production thereof and uses thereof

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10533174

    Splice-region antisense composition and method

    Sarepta Therapeutics, Inc. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10533053

    Nucleic acids encoding activatable antibodies that bind epidermal growth factor receptor

    CytomX Therapeutics, Inc. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10532032

    Rolled collagen carrier

    TAKEDA AS · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10532096

    Methods and compositions comprising a combination of a VEGF antagonist and an anti-CTLA-4 antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10532050

    Formulations of oxabicycloheptanes and oxabicycloheptenes

    Lixte Biotechnology, Inc. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10532986

    Cyclic compound acting as PDE4 inhibitor

    Medshine Discovery Inc. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10531680

    Creatine ester pronutrient compounds and formulations

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10532040

    Methods of treating cancer with herbacetin

    Regents of the University of Minnesota · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10532056

    Therapeutic compositions, combinations, and methods of use

    VERASTEM, INC. · Granted Tue Jan 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.