Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10577410

    Compositions and methods for treating and preventing Staphylococcus aureus infections

    XBIOTECH INC. · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10577406

    FKBP-L polypeptides and uses in angiogenesis-mediated disorders

    ALMAC DISCOVERY LIMITED · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10577349

    Quinolinones as inhibitors of translation initiation complex

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10577368

    A3 adenosine receptor agonists

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10577361

    Dopamine D3 receptor antagonists having a morpholine moiety

    Indivior UK Limited · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10577347

    Crystalline forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10577344

    Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins

    The Board of Regents of the University of Texas System · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10576095

    Use of aminoglycoside analogs in the treatment of Rett syndrome

    ELOXX PHARMACEUTICALS LTD. · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10576091

    Tomatidine, analogs thereof, compositions comprising same, and uses for same

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10576073

    Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10576059

    Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV

    The United States of America, as Represented by the Secretary, Department of Human Services · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10576107

    Methods of treating joint diseases, disorders, and conditions with tissue inhibitors of matrix metalloproteinases

    Prime Merger Sub, LLC · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10575537

    Saury Maillard peptide and its preparation method and application

    South China University of Technology · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10577604

    Methods for monitoring C9ORF72 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10575521

    Antimicrobial, antibacterial and spore germination inhibiting activity from an avocado extract enriched in bioactive compounds

    INSTITUTO TECNOLÓGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10576079

    Multi-drug therapies for tuberculosis treatment

    The Regents of the University of California · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10576096

    Tumor-selective combination therapy

    The Board of Regents of the University of Texas System · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10576145

    CD200 inhibitors and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10577381

    Prodrugs of 2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10577631

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10578608

    Tools to detect, track and target cancer cells in vivo

    The Regents of the University of California · Granted Tue Mar 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10584173

    Nucleic acids encoding high affinity antibodies to human IL-6 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10584161

    Monoclonal antibodies specific for heartland virus and methods of their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10584132

    SHMT inhibitors

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10584147

    Procoagulant fusion compound

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10584135

    Substituted 3,6-diazabicyclo[3.2.0]heptanes

    Indivior UK Limited · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10584105

    Immunoproteasome inhibitor analogs

    The Regents of the University of California · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10583199

    Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs

    Northwestern University · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10583202

    Homologous recombination in multipotent adult progenitor cells

    Regents of the University of Minnesota · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10584103

    Small molecule agonists of neurotensin receptor 1

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10584097

    Heterocyclic compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10583148

    Methods and devices for bone infection treatment selection

    The United States Government · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10583144

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10583180

    Method for treating adenosine deaminase severe combined imunodeficiency

    The Regents of the University of California · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10583173

    Methods of treating or preventing pruritis by blocking natriuretic polypeptide b

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10583159

    Method for increasing performance of offspring

    UNITED ANIMAL HEALTH, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10583088

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10583126

    Compositions and methods of treating cardiac fibrosis with ifetroban

    Cumberland Pharmaceuticals Inc. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10583111

    Method for preventing or treating diseases associated with the inhibition of EGFR

    ONQUALITY PHARMACEUTICALS CHINA LTD. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10582702

    Non-human animals having an engineered ANGPTL8 gene

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10583145

    Methods and compositions comprising ursolic acid and/or resveratrol for treating diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10583186

    Compositions comprising recombinant probiotic bacteria and methods of use thereof

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10583200

    Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10583134

    Methods and therapeutic combinations for treating tumors

    The Board of Regents of the University of Texas · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10584115

    Substituted pyridine and pyrazine BMI-1 inhibitors

    PTC THERAPEUTICS, INC. · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10582707

    Antimicrobial antibacterial and spore germination inhibiting activity from an avocado extract enriched in bioactive compounds

    INSTITUTO TECNOLÓGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10584355

    Chimpanzee adenoviral vector-based filovirus vaccines

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10584313

    Method of producing a differentiated mammalian cell comprising culturing a single mammalian blastomere

    Astellas Institute for Regenerative Medicine · Granted Tue Mar 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.