Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10555929

    Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy

    Coherus BioSciences, Inc. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10556875

    Bis-diazeniumdiolate compounds as anti-cancer agents

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10555997

    Antigens and vaccines directed against human enteroviruses

    SENTINEXT THERAPEUTICS Sdn Bhd · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10561662

    4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10561666

    Amido compounds as RORγt modulators and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10561729

    Near-IR light-cleavable conjugates and conjugate precursors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10562970

    Antibodies that bind colony stimulating factor 1 receptor (CSF1R)

    Five Prime Therapeutics, Inc. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10562882

    Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10563259

    Method of treatment based on polymorphisms of the KCNQ1 gene

    VANDA PHARMACEUTICALS INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10561126

    Genetically modified non-human animals and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10561606

    Injectable long-acting local anesthetic semi-solid gel formulations

    MIRA PHARMA CORPORATION · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10561744

    Multi-encapsulated formulations made with oxidized cellulose

    Covidien LP · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10563261

    Method of predicting a predisposition to QT prolongation

    VANDA PHARMACEUTICALS INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10564149

    Populations of mesenchymal stem cells that secrete neurotrophic factors

    BRAINSTORM CELL THERAPEUTICS LTD. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10563260

    Method of predicting a predisposition to QT prolongation

    VANDA PHARMACEUTICALS INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10563227

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10564161

    Method for identifying a bacterial infection

    University College Cardiff Consultants Limited · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10563094

    Coatings containing polymer modified enzyme for stable self-cleaning of organic stains

    Regents of the University of Minnesota · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10562975

    CD6 antibody for treatment of T-cell mediated diseases or disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10563183

    Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10563184

    Regulation of gene expression using engineered nucleases

    Sangamo Therapeutics, Inc. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10563204

    Methods of treating cancer harboring hemizygous loss of TP53

    The Board of Regents of the University of Texas System · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10562953

    GPR156 variants and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10562941

    Pneumolysin mutants and methods of use thereof

    The Board of Regents of the University of Oklahoma · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10562938

    Theragnostic particles

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10562930

    Salts and crystal forms of GABAA positive allosteric modulator

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10562960

    Neutralizing antibodies to gp120 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10562934

    Modulation of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10562894

    Pyrimidine compound as JAK kinase inhibitor

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10562952

    Anti-CD276 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10562886

    Anti-cancer compounds

    The Regents of the University of California · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10562884

    Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10562849

    Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

    The Board of Regents of the University of Texas System · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10562843

    Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10562850

    Human plasma kallikrein inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10561722

    Methods and compositions for enhancing immune responses

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10561761

    Polymer metal-organic framework composites

    Northwestern University · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10561724

    Live attenuated virus vaccines for La Crosse virus and other bunyaviridae

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10561732

    Trialkyl cationic lipids and methods of use thereof

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10561721

    Methods and compositions for inducing protective immunity against filovirus infection

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10561714

    Factor IX polypeptides and methods of use thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10561673

    Dendrimer based nanodevices for therapeutic and imaging purposes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10561670

    Compositions comprising acidic extracts of mastic gum

    REGENERA PHARMA LTD. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10561695

    Composition having functions of improving kidney yang, enhancing immunity and relieving fatigue, method for producing the same and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10561167

    Hypoglycemic composition and preparation method thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10562839

    Medium chain fatty acid esters of β-hydroxybutyrate and butanediol and compositions and methods for using same

    The Regents of the University of California · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10561664

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10561763

    Oxygen generating biomaterial

    The Board of Regents of the University of Texas System · Granted Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 13 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.