Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10865215

    Benzodiazepine derivatives as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10867702

    Individual and cohort pharmacological phenotype prediction platform

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10863729

    Rodents having a humanized TMPRSS gene

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10864158

    Multilayer thin film drug delivery device and methods of making and using the same

    The Regents of the University of California · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10864168

    Bioactive delivery vehicles

    The Regents of the University of California · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10864175

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    TONIX PHARMA LIMITED · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10864153

    Compositions and methods for blocking ultraviolet radiation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10864222

    Beta-lactamase inhibitors, formulations, and uses thereof

    The Regents of the University of California · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10864176

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    TONIX PHARMA LIMITED · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10864235

    Synergistic bacterial compositions and methods of production and use thereof

    Seres Therapeutics, Inc. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10864181

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10864217

    Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10864223

    Lipid compositions

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10864252

    Anti-SSX-2 T cell receptors and related materials and methods of use

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10864256

    Methods and compositions for improved cognition

    The Regents of the University of California · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10864266

    Modified lipopolysaccharide glycoform and method of use

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10864276

    Activated polyoxazolines and conjugates and compositions comprising the same

    Serina Therapeutics, Inc. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10865186

    Opioid agonists and uses thereof

    Nektar Therapeutics · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10865200

    Nitrogen-containing heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10864304

    Anti-infective antimicrobial-containing biomaterials

    ATRIUM MEDICAL CORPORATION · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10865211

    Functionalized heterocycles as antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10865389

    DNA vaccines against foot-and-mouth disease virus

    The Government of the United States of America, as represented by the Secretary of Homeland Security · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10865378

    Thin film cell encapsulation devices

    The Regents of the University of California · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10865226

    Peptide showing melanogenesis promoting activity and use thereof

    CAREGEN CO., LTD. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10865236

    Bispecific antigen-binding molecules that bind a staphylococcus target antigen and a complement component and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10865387

    Methods of obtaining pancreatic endocrine cells

    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN REGENT WALK · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10865400

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. WO 2020249818

    PROCÉDÉ DE TRAITEMENT DU CANCER PAR DÉPÔT INTRATUMORAL DE MICROPARTICULES RADIOACTIVES

    ADVANCED ACCELERATOR APPLICATIONS [FR] · Granted Thu Dec 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10869863

    Multi-arm polymeric targeting anti-cancer conjugate

    BrightGene Bio-Medical Technology Co., Ltd. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10869841

    Nanoscale coatings for encapsulation of biological entities

    The Regents of the University of California · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10869846

    N-acetylcysteine amide (NAC amide) in the treatment of diseases and conditions associated with oxidative stress

    SENTIENT LIFESCIENCES, INC. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10869856

    Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10870679

    Modulation of structured polypeptide specificity

    BicycleRD Limited · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10870842

    Stabilized alpha-galactosidase and uses thereof

    Protalix Ltd. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10870673

    β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment

    Atea Pharmaceuticals, Inc. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10870687

    Anti-human papillomavirus 16 E7 T cell receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10870837

    Fusion proteins comprising enzyme replacement therapy enzymes

    DENALI THERAPEUTICS INC. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10870854

    Inhibitory RNA-based therapeutics targeting ANLN for cancer treatment

    The Board of Regents of the University of Texas System · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10869865

    Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria

    The United States of America, as represented by the Secretary, Department of Health and Human Serv · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10869902

    Cured gel and method of making

    ATRIUM MEDICAL CORPORATION · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10869851

    Targeting NUR77 for mitigating perinatal neuroinflammation

    United States Government as represented by the Secretary of the Army · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10870855

    Use of MIR101 or MIR128 in the treatment of seizure disorders

    OVID THERAPEUTICS INC. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10870672

    β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment

    Atea Pharmaceuticals, Inc. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10869920

    Construction of West Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by West Nile virus

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10869901

    Hydrolyzed chicken sternal cartilage extract, method for producing the same and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10869911

    Chimeric protein

    AUTOLUS LIMITED · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10870645

    Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors

    Valo Early Discovery, Inc. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10870625

    Zwitterionic propargyl-linked antifolates useful for treating bacterial infections

    UNIVERSITY OF CONNECTICUT · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.