Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10781450

    Antisense molecules and methods for treating pathologies

    Sarepta Therapeutics, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10781422

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10781242

    Interleukin-2 fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10781189

    1,2,4-Oxadiazole and thiadiazole compounds as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10781251

    Monoclonal antibodies to growth and differentiation factor 15 (GDF-15)

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10781255

    Anti-CD83 antibodies and use thereof

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10781435

    Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use

    Catalyst Biosciences, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10781218

    Substituted inhibitors of menin-MLL and methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10780155

    Streptococcal GlcNac-lacking gylcopolypeptides, cell wall carbohydrates, Streptococcus vaccines, and methods for making and using them

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10780096

    Pyrrolobenzodiazepine-antibody conjugates

    ADC THERAPEUTICS SA · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10780095

    Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10780067

    Endoxifen for local transdermal therapy to the breast

    Northwestern University · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10780058

    Nucleic acid nanocapsules for drug delivery and targeted gene knockdown

    UNIVERSITY OF CONNECTICUT · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10780166

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10781208

    5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10780074

    Compounds and uses thereof

    PGI Drug Discovery LLC · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10779517

    Animal wound model and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10788490

    Dried cellulose-treated tissue for in-vitro complement activation assays and diagnostic kits

    ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10785966

    Humanized M-CSF mice

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10786501

    Treatment of prostate cancer

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10786435

    Composition for optical three-dimensional modeling

    KURARAY NORITAKE DENTAL INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10786495

    Vesicular monoamine transporter 2 inhibitors for treating stuttering

    The Regents of the University of California · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10786438

    Recombinant nucleic acids encoding cosmetic protein(s) for aesthetic applications

    Krystal Biotech, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10786461

    Onapristone extended-release compositions and methods

    CONTEXT BIOPHARMA, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10786512

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10786566

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10786545

    Use of peptides that block metadherin-SND1 interaction as treatment for cancer

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10786554

    Factor VIII polypeptide formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10787452

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10786582

    Gd(III)-dithiolane gold nanoparticle conjugates

    Northwestern University · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10787419

    Cannabinoid receptor mediating iminopyrazole compounds

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10787446

    Therapeutic compounds and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10787439

    Compounds and methods for activating the apoptotic arm of the unfolded protein response

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10787449

    Octahydro fused azadecalin glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10787462

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10787647

    HSD17B13 variants and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10787499

    EpCAM targeted polypeptides, conjugates thereof, and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10787501

    Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10787472

    Prodrugs of pyridone amides useful as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10785968

    Genetically modified non-human animals and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10786520

    Aminoglycoside derivatives and uses thereof in treating genetic disorders

    ELOXX PHARMACEUTICALS LTD. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10786552

    Il-2Rβ-selective agonists in combination with an anti-CTLA-4 antibody or an anti-PD-1 antibody

    Nektar Therapeutics · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10787413

    Derivatives of curcuminoids and use thereof as an anticancer agent

    China Medical University · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10787490

    Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

    Protagonist Therapeutics, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. CA 3133787

    GELS HOMOGENES INJECTABLES COMPRENANT DE MULTIPLES FORMES D'ACIDE HYALURONIQUE ET LEURS PROCEDES DE FABRICATION

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Oct 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 26 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10792481

    Implantable drug delivery device

    Nano Precision Medical, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10791731

    Methods for preparing frozen plasma material for rapid thawing in an emergency situation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10792246

    Film formulations containing dexmedetomidine and methods of producing them

    BioXcel Therapeutics, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.