Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10759813

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 10759905

    Biodegradable amphiphilic polymer, polymeric vesicles prepared therefrom, and application of biodegradable amphiphilic polymer in preparation of medicines for targeted therapy of lung cancer

    BrightGene Bio-Medical Technology Co., Ltd. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 10760076

    Use of single-stranded antisense oligonucleotide in prevention or treatment of genetic diseases involving a trinucleotide repeat expansion

    ProQR Therapeutics II B.V. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 2020276276

    PTH Prodrugs

    ASCENDIS PHARMA BONE DISEASES AS [DK] · Granted Thu Sep 03 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 29 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 10765727

    Compositions and methods for producing dendritic cells

    PrimeVax Immuno-Oncology · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 10767179

    MicroRNA composition for the treatment of neuroblastoma

    The Board of Regents of the University of Texas System · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 10765760

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 10766892

    GLS1 inhibitors for treating disease

    The Board of Regents of the University of Texas System · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 10765666

    Use of gaboxadol for the treatment of Tourette syndrome, tics and stuttering

    OVID THERAPEUTICS INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 10765694

    Compositions and methods for delivering inhibitory oligonucleotides

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 10766864

    Morphinan derivatives for the treatment of neuropathic pain

    Nektar Therapeutics · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 10766869

    Triazoles for the treatment of demyelinating dieases

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 10766902

    Wee-1 inhibiting pyrazolopyrimidinone compounds

    ALMAC DISCOVERY LIMITED · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 10766925

    Opioid receptor modulators

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 10766908

    Calcium L-lactate frameworks as naturally degradable carriers

    The Regents of the University of California · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 10766927

    Peptides that stimulate subcutaneous adipogenesis

    The Regents of the University of California · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10765705

    Visco-supplement compositions, and methods of use thereof

    Prime Merger Sub, LLC · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10765759

    Methods of treating an ocular disease or disorder

    The Regents of the University of California · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10765683

    Stable formulations for parenteral injection of small molecule drugs

    XERIS PHARMACEUTICALS, INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10766877

    Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 10765636

    Mesoporous silica nanoparticles with a lipid bilayer coating for cargo delivery

    The Regents of the University of California · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 10765600

    Adapter for use in a planetary mixer

    MEDISCA PHARMACEUTIQUE INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 10765646

    Methods of treating developmental encephalopathies

    OVID THERAPEUTICS INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 10765627

    Immunogenic composition against Campylobacter jejuni

    United States of America as represented by the Secretary of the Air Force · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 10765762

    Humanized model of kidney and liver disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 10766890

    Hepatitis B core protein modulators

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 10766858

    Substituted benzamides and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 10765776

    Tissue-derived biomaterial composition and methods for ocular and other therapeutic applications

    SOUTH DAKOTA BOARD OF REGENTS (SDBOR) · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 10765687

    Methods and compounds to inhibit enveloped virus release

    Northwestern University · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 10766903

    Piperidine derivatives as inhibitors of ubiquitin specific protease 7

    ALMAC DISCOVERY LIMITED · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 10767177

    Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 10768167

    Plasma membrane citrate transporter for use in the diagnosis and treatment of cancer

    UNIVERSITÄTSKLINIKUM REGENSBURG · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 10767184

    Chimeric antigen receptors targeting B-cell maturation antigen

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 10765745

    Multifunctional nanoparticle systems and methods for cancer diagnosis and combination therapy

    The Board of Regents of the University of Texas System · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 10765691

    Method for treating crohn's disease using triple antimicrobial all-in-one formulation

    RedHill Biopharma Ltd. · Granted Tue Sep 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. WO 2020178316

    AZAINDAZOLES EN 5 OU 7 UTILISÉS COMME INHIBITEURS DE BÊTA-LACTAMASE

    ACRAF [IT] · Granted Thu Sep 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. CA 3131817

    FORMES POSOLOGIQUES D'HORMONE DE CROISSANCE A ACTION PROLONGEE AYANT UNE EFFICACITE SUPERIEURE A UNE DOSE DE SOMATROPINE QUOTIDIENNE

    ASCENDIS PHARMA ENDOCRINOLOGY DIV A/S [DK] · Granted Thu Sep 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 10772942

    Lyophilized factor IX formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 10772959

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 10772960

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 10772963

    Etanercept formulations stabilized with xylitol

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 10772971

    Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates

    Mersana Therapeutics, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 10774066

    Prodrugs of NRF2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 10774083

    Heterocyclic amide compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 10774181

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 10774118

    Peptides having reduced toxicity that stimulate cholesterol efflux

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 10774121

    Methods and compositions for treating neurodegenerative disorders and Alzheimer's Disease and improving normal memory

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 10774128

    IL-33 antagonists and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.