Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10703816

    M971 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10702535

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10702532

    Nucleotide analogs

    The Regents of the University of California · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10702474

    Fusogenic liposome-coated porous silicon nanoparticles

    The Regents of the University of California · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10703698

    Compounds which activate estrogen receptors and compositions and methods of using the same

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10703721

    Caffeic acid derivatives and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10703746

    Mutant IDH1 inhibitors useful for treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10704076

    Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm

    Government of the United States, as represented by the Secretary of the Air Force · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10703805

    Molecular imprinting of West Nile antibodies with physiological pH matching

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. HR P20200591

    ANTIBODIES SPECIFIC FOR CLAUDIN 6 (CLDN6)

    ASTELLAS PHARMA INC [JP] · Granted Fri Jul 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10709733

    Nonsurgical techniques for restoring tooth enamel

    Regents of the University of Minnesota · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10709739

    Method for chemoselection

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10709790

    Chemical conjugates of Evans Blue derivatives and their use in the production of long-acting therapeutics

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10709799

    Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10711257

    Modified cascade ribonucleoproteins and uses thereof

    Caribou Biosciences, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10710958

    Carbamoyl phenylalaninol compounds and uses thereof

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10710983

    2,4-diamino-pyrimidine compounds and method for making and using the compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10710989

    Method for producing heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10709813

    Solubilization of antigen components for removal from tissues

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10711007

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Prelude Therapeutics, Incorporated · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10711032

    Steroids and protein-conjugates thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10711292

    Method for promoting the synthesis of collagen and proteoglycan in chondrocytes

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10711068

    Anti-CD133 monoclonal antibodies and related compositions and methods

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10709812

    Biodegradable hydrogel for tissue expansion

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10711029

    Beta-d-2′-deoxy-2′-alpha-fluoro-2′-beta-c-substituted-4′fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection

    Atea Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10709758

    Peptide inhibitors of clostridium difficile toxin B (TcdB) toxin

    The Board of Regents of the University of Oklahoma · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10711312

    Methods for immunotherapy-based treatment and assessment of cancer

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10711314

    Methods for diagnosing IDH-mutant cell proliferation disorders

    Agios Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10709703

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10709665

    Zinc meloxicam complex microparticle multivesicular liposome formulations and processes for making the same

    Pacira Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10709705

    Aminopyrimidines as ALK inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10709692

    Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1)

    DENALI THERAPEUTICS INC. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10709728

    Polynucleotide agents targeting angiotensinogen (AGT) and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10711028

    Antimicrobial compounds, compositions, and uses thereof

    Lakewood Amedex, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10716770

    Nicotinic receptor non-competitive antagonists

    Catalyst Biosciences, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10718778

    Compositions and methods for detecting protein sulfenylation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10717981

    Therapeutic compositions and methods of making and using the same

    Advanced ReGen Medical Technologies, LLC · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10717765

    Compositions and methods for treating autoimmune and inflammatory disorders

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10717764

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10717993

    Methods and compositions for increased transgene expression

    Sangamo Therapeutics, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10717748

    1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10717732

    Inhibitors of influenza virus replication, application methods and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10716860

    Cochleates made with soy phosphatidylserine

    MATINAS BIOPHARMA NANOTECHNOLOGIES, INC. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10716856

    Engineered primate cystine/cysteine degrading enzymes as antineogenic agents

    The Board of Regents of the University of Texas System · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10716854

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10716851

    Agonist antibodies that bind human CD137 and uses thereof

    Compass Therapeutics LLC · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10716843

    Immune enhancing recombinant dengue protein

    United States of America as represented by the Secretary of the Air Force · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10716853

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.