Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10610520

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Apr 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. EP 3630112

    KOMBINATION AUS REGORAFENIB UND PD-1/PD-L1(2)-INHIBITOREN ZUR BEHANDLUNG VON KREBS

    BAYER AG [DE] · Granted Wed Apr 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Apr 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10617737

    Compositions for treating heart disease by inhibiting the action of mAKAP-β

    Anchored RSK3 Inhibitors, LLC · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10618968

    Antigen-binding proteins that activate the leptin receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10618967

    Anti-CSF1R antibody and anti PD-1 antibody combination therapy for cancer

    Five Prime Therapeutics, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10619157

    Cancer treatment

    Ionis Pharmaceuticals, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10618877

    Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid

    PTC THERAPEUTICS, INC. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10617709

    miRNAs as novel therapeutic adjuvants and biomarkers for the prognosis and treatment of drug resistant breast cancers

    The Board of Regents of the University of Texas System · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10617663

    Dosage forms and therapeutic uses of L-4-chlorokynurenine

    VISTAGEN THERAPUETICS, INC. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10617673

    Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes

    Jenrin Discovery, LLC · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10617642

    Sustained release formulation of a non-steroidal anti-inflammatory drug

    Pacira Pharmaceuticals, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10617747

    Peptide conjugated particles

    Northwestern University · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10617674

    Dosage regimen for the treatment of acute exacerbations of inflammatory conditions

    MEREO BIOPHARMA 1 LIMITED · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10617681

    1-arylalkyl-4-acylaminopiperidine compounds

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10617706

    Compounds for cancer chemotherapeutic sensitization

    Regents of the University of Minnesota · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10617707

    Oligonucleotides to treat eye disease

    ProQR Therapeutics II B.V. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10619158

    Modulation of huntingtin expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10619160

    Compositions and methods for inhibiting expression of RRM2 genes

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10618983

    Hyaluronic acid-based hydrogels having medical applications

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10617757

    Methods for treating multiple myeloma

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10619153

    TAL effector-mediated DNA modification

    Regents of the University of Minnesota · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10619154

    Nuclease-mediated regulation of gene expression

    Sangamo Therapeutics, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10619156

    Hybrid tRNA/pre-miRNA molecules and methods of use

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10620204

    Antibody-mediated neutralization of Ebola viruses

    The Board of Regents of the University of Texas System · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10617136

    Calcium oxide compound with high purity

    ARKIM KIMYEVI MADDELER SANAYI VE TICARET ANONIM SIRKETI · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10618869

    Oligo-benzamide compounds and their use

    The Board of Regents of the University of Texas System · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10618938

    Compositions for colon cleansing and the treatment of gastrointestinal disorders

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10617667

    Method for treating brain tumors

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10617740

    Methods of treating mild brain injury

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10617723

    C. novyi for the treatment of solid tumors in humans

    Biomed Valley Discoveries, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10618972

    Antibodies for botulinum neurotoxins

    The Regents of the University of California · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10618908

    Oxabicycloheptane prodrugs

    Lixte Biotechnology, Inc. · Granted Tue Apr 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. WO 2020074463

    COMPOSITION LIQUIDE ORALE COMPRENANT DU TRIPTAN

    ACRAF [IT] · Granted Thu Apr 16 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 11 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. CA 3112060

    COMPOSITION PHARMACEUTIQUE COMPRENANT UN ANTAGONISTE DE GPRP RADIOMARQUE ET UN TENSIOACTIF

    ADVANCED ACCELERATOR APPLICATIONS INT SA [CH] · Granted Thu Apr 16 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 11 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10624959

    Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10624849

    Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites

    Northwestern University · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10626372

    Methods and compositions for inducing hematopoietic cell differentiation

    Fate Therapeutics, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10626469

    Rapid identification of microorganisms

    BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE OF THE UNIVERSITY OF NEVADA, RENO · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10624850

    Emulsion formulations of an NK-1 receptor antagonist and uses thereof

    Heron Therapeutics, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10624379

    Composition, method for producing the same and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10626399

    Methods of treating cognitive symptoms of an aging-associated impairment by modulating C-C chemokine receptor type 3 (CCR3)

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10627409

    Therapeutic antibodies against ROR-1 protein and methods for use of same

    The Regents of the University of California · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10626146

    α4β7 thioether peptide dimer antagonists

    Protagonist Therapeutics, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10626094

    Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10624887

    Compositions of (-)-17-(cyclobutylmethyl)morphinan-3,14,-diol

    Relmada Therapeutics, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10626129

    Heteroaryl inhibitors of PDE4

    Tetra Discovery Partners · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10624878

    Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs

    Olema Pharmaceuticals, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10626396

    Antisense composition and method for treating muscle atrophy

    Sarepta Therapeutics, Inc. · Granted Tue Apr 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.