Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10189809

    SGC stimulators

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10188644

    Process of making stable abuse-deterrent oral formulations

    Collegium Pharmaceutical, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10188714

    Yeast-MUC1 immunotherapeutic compositions and uses thereof

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10188755

    Magnetic microstructures for magnetic resonance imaging

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10188711

    Peptide conjugated particles

    Northwestern University · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10188751

    Papillomavirus pseudoviruses for detection and therapy of tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10188650

    Treatment of neurological disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10188656

    Methods of treatment of malignancies

    Agios Pharmaceuticals, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10188769

    Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10189901

    Methods for improving cardiac function by administering an antibody that activates APLNR

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10189846

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10190097

    Method and composition for inducing human pluripotent stem cells

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10189784

    N-(5-((aryl or heteroaryl)methyloxy)pentyl)-substituted iminosugars as inhibitors of glucosylceramide synthase

    ACADEMISCH MEDISCH CENTRUM · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10188461

    Selective fat removal using photothermal heating

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10189859

    Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine

    Nektar Therapeutics · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10190129

    Increasing levels of nicotinic alkaloids in plants

    22ND CENTURY LIMITED, LLC · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10189881

    MPS peptides and use thereof

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10190118

    Methods and compositions for treating insects

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10189825

    Heteroaryl compounds and methods of use thereof

    PGI Drug Discovery LLC · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10189878

    Ebolavirus pre-hairpin intermediate mimics and methods of use

    The United States of America—Air Force · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10189872

    Crystalline form of nicotinamide riboside

    W.R. Grace & Co.-Conn. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10188633

    Identification of small molecules that facilitate therapeutic exon skipping

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10188608

    Oxidized cellulose microspheres

    Covidien LP · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10188619

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10189785

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10195291

    Compositions and methods for the manufacture of lipid nanoparticles

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10195612

    Small particle compositions and associated methods

    Primet Precision Materials, Inc. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10195151

    Formulations of (R)-2-amino-3-phenylpropyl carbamate

    Jazz Pharmaceuticals International III Limited · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10195236

    Use of gram negative species to treat atopic dermatitis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10196372

    MYC G-quadruplex stabilizing small molecules and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10197577

    Serum antibody assay for determining protection from malaria, and pre-erythrocytic subunit vaccines

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10195168

    Gamma-hydroxybutyrate compositions and their uses for the treatment of disorders

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10195202

    Methods for modulating the amount of RNA transcripts

    PTC THERAPEUTICS, INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10195222

    Acyclic nucleoside phosphonate diesters

    The Regents of the University of California · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10196377

    Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

    OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU “PHARMENTERPRISES” · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10196613

    Stem cells for modeling type 2 diabetes

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10196443

    TEM8 antibodies and their use in treatment and detection of tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10196378

    Inhibitors of BCR-ABL mutants and use thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10195297

    Iron garnet nanoparticles for cancer radiotherapy and chemotherapy

    The Board of Regents of the University of Texas System · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10195214

    Concomitant administration of glucocorticoid receptor modulators and CYP3A inhibitors

    Corcept Therapeutics Incorporated · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10195259

    Compositions and methods for treatment of cancer using bacteria

    Decoy Biosystems, Inc. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10196356

    Mixed disulfide conjugates of thienopyridine compounds and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10196425

    Peptide compositions

    RHYTHM PHARMACEUTICALS, INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10195165

    Methods of treating Prader-Willi syndrome

    OVID THERAPEUTICS INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10195278

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10195275

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10195279

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10196383

    Substituted quinazoline compounds and preparation and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.