Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10400010

    Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics

    The Regents of the University of California · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10400006

    Estrogen receptor modulators

    The Regents of the University of California · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10399994

    Compounds and methods for preventing or treating sensory hair cell death

    Oricula Therapeutics LLC · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10399962

    Azolopyrimidine for the treatment of cancer-related disorders

    Arcus Biosciences, Inc. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10399943

    Antifungal compound process

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10398778

    Method for enhancing specific immunotherapies in cancer treatment

    Providence Health & Services—Oregon · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10399937

    Ionizable cationic lipid for RNA delivery

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10398776

    Phonophoretic cannabidiol composition and transdermal delivery system

    Essential Green Goodness LLC · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10399189

    Airfoil aerodynamics

    UNITED TECHNOLOGIES CORPORATION · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10398769

    Influenza nucleic acid molecules and vaccines made therefrom

    Inovio Pharmaceuticals, Inc. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10398762

    Methods and compositions for treating diabetes

    Oramed Ltd. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10398721

    Methods for treating progeroid laminopathies using oligonucleotide analogues targeting human LMNA

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10398708

    Vaginal inserted estradiol pharmaceutical compositions and methods

    Compass Therapeutics LLC · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10398668

    Glutamate treatment of cardiovascular disorders

    The Board of Regents of the University of Oklahoma · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10398682

    Methods and compositions to prevent or treat bacterial infections

    The Board of Regents of the University of Texas System · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10398661

    Methods for classifying a cancer as susceptible to TMEPAI-directed therapies and treating such cancers

    The Board of Regents of the University of Texas System · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10398686

    Compositions of a polyorthoester and an aprotic solvent

    Heron Therapeutics, Inc. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10398784

    Nanoconjugates able to cross the blood-brain barrier

    Northwestern University · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10399963

    Substituted benzofuranyl and benzoxazolyl compounds and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10398648

    Method for formulating large diameter synthetic membrane vesicles

    Pacira Pharmaceuticals, Inc. · Granted Tue Sep 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. CA 3091946

    EXPANSION ET DIFFERENCIATION DE CELLULES SOUCHES

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Fri Sep 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Sep 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10407405

    Nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10406125

    Combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof and a compound able to increase the H2O2 level in cancer cells of a subject

    ADVANCED BIODESIGN · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10406148

    Methods of treatment using a JAK inhibitor compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10406158

    Methods and compositions for treating abnormal cell growth

    VERASTEM, INC. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10406169

    Methods of monitoring estriol therapy

    The Regents of the University of California · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10406194

    Powder formulation, method for preparing the same and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10406225

    Anti-EphA2 antibodies and methods of use thereof

    The Regents of the University of California · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10406226

    Method of manufacturing VEGF antagonist fusion proteins

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10407392

    Antifungal compound process

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10407409

    6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10407443

    5-HT3 receptor antagonists

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10407466

    Methods of selecting compstatin mimetics

    Apellis Pharmaceuticals, Inc. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10407484

    Compositions and methods for modulating T-cell mediated immune response

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10408834

    Mutated parvovirus structural proteins as vaccines

    Ludwig-Maximilians-Universitat Munchen · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10405560

    Method for making coffee products containing cannabis ingredients

    Blacklist Holdings, Inc. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10406160

    Sustained release small molecule drug formulation

    Indivior UK Limited · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10406146

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10406157

    Tetrahydropyridopyrazine modulators of GPR6

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10406167

    Texaphyrin-Pt(IV) conjugates and compositions for use in overcoming platinum resistance

    The Board of Regents of the University of Texas System · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10406214

    Propionyl-CoA carboxylase compositions and uses thereof

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10406177

    Modified cells and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10406210

    High-purity inhalable particles of insulin and insulin analogues, and high-efficiency methods of manufacturing the same

    Amphastar Pharmaceuticals, Inc. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10406222

    Human antibodies to Middle East Respiratory Syndrome—coronavirus spike protein

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10406233

    Telodendrimers with enhanced drug delivery

    The Regents of the University of California · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10406249

    Gd(III)-dithiolane gold nanoparticle conjugates

    Northwestern University · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10406241

    Hydrogel prodrug for treatment

    Viking Scientific, Inc. · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10406248

    Molecular imaging of cancer cells in vivo

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Sep 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.