Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10351580

    Acene-based transmitter molecules for photon upconversion

    The Regents of the University of California · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10351618

    UTI fusion proteins

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10350312

    Magnetic microstructures for magnetic resonance imaging

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10350265

    Therapeutic applications of Smad7

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10351628

    Antibody fragments, compositions and uses thereof

    METIS PRECISION MEDICINE SB S.R.L. · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10351598

    Peptide with anti-obesity and anti-diabetic efficacy and use thereof

    CAREGEN CO., LTD. · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10351587

    Method of making and using 7α, 11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10350273

    Treatment of hormonal disorders of growth

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10350228

    Treatment of sickle cell disease and inflammatory conditions

    Regents of the University of Minnesota · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10350267

    Polypeptide-polymer conjugates and methods of use thereof

    The Regents of the University of California · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10350256

    Compositions for the treatment of dermatological conditions, disorders or diseases

    Veit Hoermann Gesellschaft Für Unternehmenskommunikation mbH · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10350306

    Methods and compositions for treating genetically linked diseases of the eye

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10350292

    Agonist antibodies that bind human CD137 and uses thereof

    Compass Therapeutics LLC · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10350296

    Chewable gelatin formulations

    Aspire Pharmaceuticals · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10351522

    Sulfonamide derivative and pharmaceutically acceptable acid addition salt thereof

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10351532

    Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10351547

    Somatostatin modulators and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10351589

    3.alpha.-ethynyl, 3.beta.-hydroxy-5.alpha.-pregnan-20-oxime for use in the treatment of CNS disorders

    Umecrine Cognition AB · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10351597

    Peptide with anti-obesity and anti-diabetes activity and use thereof

    CAREGEN CO., LTD. · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10351606

    Mutated Salmonella enterica

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10351844

    Methods and compositions for treating leber congenital amaurosis

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10351878

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10350170

    Solid preparation

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10350163

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10350183

    Intravenous baclofen formulations and treatment methods

    Regents of the University of Minnesota · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10350193

    Super-oxide dismutase mimetics

    Galera Labs, LLC · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10350162

    Methods and compositions for oral administration of exenatide

    Oramed Ltd. · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10350249

    Reduction of milk glycans and their degradation products in the neonate gut

    The Regents of the University of California · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10350239

    Pharmaceutical composition for treating cancer comprising trypsinogen and/or chymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compound and a cytoplasmic glycolysis reduction agent

    Propanc Pty Ltd · Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. CA 3088180

    COMPOSITIONS ET METHODES POUR L'EDITION GENIQUE PAR CIBLAGE DE LA TRANSFERRINE

    CRISPR THERAPEUTICS AG [CH] · Granted Thu Jul 18 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 13 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10358419

    1,3-dipolar [70]fulleropyrrolidinium iodide derivatives

    The Board of Regents of the University of Texas System · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10357448

    Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi

    The Board of Regents of the University of Texas System · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10357453

    Methods of eye treatment using therapeutic compositions containing dipyridamole

    O.D. Ocular Discovery Ltd. · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10357460

    Particulate comprising a calcium-containing compound and a sugar alcohol

    TAKEDA AS · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10357217

    Method for positron emission tomography (PET) imaging analysis for classifying and diagnosing of neurological diseases

    The Regents of the University of California · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10357465

    Eutectic formulations of cyclobenzaprine hydrochloride

    TONIX PHARMA LIMITED · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10357484

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10357510

    Metal nanoclusters and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10357522

    Bacteriophage compositions and methods of selection of components against specific bacteria

    United States of America as represented by the Secretary of the Air Force · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10357539

    Use of peptides that block metadherin-SND1 interaction as treatment for cancer

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10357477

    Anticancer compounds

    Regents of the University of Minnesota · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10357565

    Targeting microbubbles

    The Regents of the University of California · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10357464

    Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief

    The Board of Regents of the University of Texas System · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10358659

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10357554

    AMA-1 epitopes, antibodies, compositions, and methods of making and using the same

    The United States of America as represented by the Secretary of the Army · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10358658

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10358433

    Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity

    Theravance Respiratory Company, LLC · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10358439

    DNA binding agents with a minor groove binding tail

    The Board of Regents of the University of Texas System · Granted Tue Jul 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.