Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10285945

    Formation of stable submicron peptide or protein particles by thin film freezing

    The Board of Regents of the University of Texas System · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10285978

    Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10287286

    Compounds

    Takeda Pharmaceutical Company Limited · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10285935

    Non-invasive method for direct delivery of therapeutics to the spinal cord in the treatment of spinal cord pathology

    United States Department of Veteran Affairs · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10285996

    Compositions comprising triterpenoids

    REGENERA PHARMA LTD. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10286031

    Method of manufacture of GnRH-containing gel

    United-AH II, LLC · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10287279

    Inhibitors of human 12/15-lipoxygenase

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10286054

    Attenuated EHEC and clostridial toxins TcdA and TcdB based vaccine for Clostridium difficil associated disease (CDAD)

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10286065

    Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds

    The Board of Regents of the University of Texas System · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10285986

    Compounds and anti-tumor NQO1 substrates

    The Board of Regents of the University of Texas System · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10286072

    Methods of manufacturing stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10286036

    Protocol for treatment of lupus nephritis

    AURINIA PHARMACEUTICALS INC. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10286044

    Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof

    HALOZYME, INC. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10286077

    Steroid hormone compositions in medium chain oils

    Compass Therapeutics LLC · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10287584

    Compounds and methods for the modulation of COMP

    The Board of Regents of the University of Texas System · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10287564

    Procoagulant compounds

    BIOVERATIV THERAPEUTICS INC. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10287355

    Methods and compositions for modulating lymphangiogenesis, E.G., to treat transplant rejection, in a subject

    The Regents of the University of California · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10287297

    Epoxyazulene derivatives useful for treating cancer and diabetes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10287596

    Regulating alkaloids

    22ND CENTURY LIMITED, LLC · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10287262

    Eicosanoid derivatives

    The Board of Regents of the University of Texas System · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10287305

    Substituted piperidine compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10287582

    Organic compositions to treat HSF1-related diseases

    Arrowhead Pharmaceuticals, Inc. · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10287572

    Protein scaffolds and methods of use

    Regents of the University of Minnesota · Granted Tue May 14 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 2019144465

    Macrocyclic MCL-1 inhibitors and methods of use

    ABBVIE INC [US] · Granted Thu May 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10293037

    DNA vaccine for use in pancreatic cancer patients

    Vaximm AG · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10293002

    Methods and compositions for in vivo induction of pancreatic beta cell formation

    The Board of Regents of the University of Texas System · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10294296

    Treatment for neoplastic diseases

    XBIOTECH INC. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10293080

    Ionic liquids that sterilize and prevent biofilm formation in skin wound healing devices

    Arizona Board of Regents on Behalf of Northern Arizona University · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10293056

    Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases

    The Board of Regents of the University of Texas System · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10294274

    Polypeptide ligands specific for plasma kallikrein

    BicycleRD Limited · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10292951

    Methods and compositions for treating conditions associated with an abnormal inflammatory responses

    First Wave Bio, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10292986

    Methods for treating epithelian mesenchymal transition related diseases

    The Board of Regents of the University of Texas System · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10294477

    Compositions and methods for modulating PKK expression

    Ionis Pharmaceuticals, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10294483

    Eimeria tenella elongation factor-1 alpha recombinant immunogenic compositions which induce active protective immunity against avian coccidiosis

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10292979

    Methods of treating cancer patients with farnesyltransferase inhibitors

    Kura Oncology, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10294474

    Targeting ligands

    Arrowhead Pharmaceuticals, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10294277

    Stabilised FMDV capsids

    The Pirbright Institute · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10293077

    Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use

    The Regents of the University of California · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10294215

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10293005

    Use of gram negative species to treat atopic dermatitis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10292940

    Hyaluronic acid-based amphiphilic polymer, preparation method and application thereof

    BrightGene Bio-Medical Technology Co., Ltd. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10292971

    Tetrahydro-1H-pyrido[3,4-b]indole anti-estrogenic drugs

    Olema Pharmaceuticals, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10293000

    Methods and compositions for the treatment of lysosomal storage diseases

    Sangamo Therapeutics, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10292992

    Selective high-affinity polydentate ligands and methods of making such

    The Regents of the University of California · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10293022

    Peptide inhibitors of serotonin 5-HT2C receptor:PTEN interaction

    THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYTEM · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10293012

    Methods of using extracts of melissa officinalis against filoviruses

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10293049

    Etanercept formulations stabilized with amino acids

    Coherus BioSciences, Inc. · Granted Tue May 21 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. EP 3485879

    ORALE PHARMAZEUTISCHE FORMULIERUNG ENTHALTEND BAKTERIEN

    MAAT PHARMA [FR] · Granted Wed May 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.