Wednesday, July 8, 2026

Drug profile · INN

ziv-aflibercept

ziv-aflibercept (ZALTRAP) is a placenta growth factor inhibitor. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 10
News articles 0
Drug details — ziv-aflibercept
US status
approved
Class
Route
INJECTION
Patents
0
Programs
10
Data quality
0.84

Quick answer

ziv-aflibercept (ZALTRAP) is a placenta growth factor inhibitor. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ziv-aflibercept
Brand ZALTRAP
Mechanism Placenta growth factor inhibitor
Target Placenta growth factor
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Placenta growth factor inhibitor

Primary target: Placenta growth factor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. EFC10261 Phase 3 · Regeneron UK · Carcinoma
  2. EFC10547 Phase 3 · Regeneron UK · Pancreatic Neoplasm
  3. EFC6125 Phase 3 · Regeneron UK · Ovarian Neoplasms
  4. ARD6122 Phase 2 · Regeneron UK · Neoplasms
  5. ARD6123 Phase 2 · Regeneron UK · Pulmonary Diseases
  6. Calcio levofolinato Teva Generics polvere per... Phase 2 · Telethon Foundation · Patients with metastatic colorectal cancer (mCRC) RAS-mutant
  7. ZIV-Aflibercept Phase 2 · Regeneron UK · Metastatic Uveal Melanoma
  8. Ziv-Aflibercept Phase 2 · Regeneron UK · Uveal Melanoma

Related & competitor drugs

  1. aflibercept Sensory organs (S01)
  2. aflibercept-abzv Placenta growth factor inhibitor
  3. aflibercept-ayyh Placenta growth factor inhibitor
  4. aflibercept-jbvf Placenta growth factor inhibitor
  5. aflibercept-mrbb Placenta growth factor inhibitor
  6. aflibercept-yszy Placenta growth factor inhibitor

Frequently asked questions

What is ziv-aflibercept?

ziv-aflibercept (ZALTRAP) is a placenta growth factor inhibitor. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ziv-aflibercept?

ZALTRAP is a marketed brand name for ziv-aflibercept. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ziv-aflibercept?

ziv-aflibercept has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.