Wednesday, July 8, 2026

Drug profile · INN

zavegepant hydrochloride

zavegepant hydrochloride (ZAVZPRET) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: nasal. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — zavegepant hydrochloride
US status
approved
Class
Route
NASAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

zavegepant hydrochloride (ZAVZPRET) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: nasal. Current US regulatory status: approved.

Key facts

INN zavegepant hydrochloride
Brand ZAVZPRET
Mechanism Calcitonin gene-related peptide type 1 receptor antagonist
Target Calcitonin gene-related peptide type 1 receptor
Route NASAL
Formulation SPRAY, METERED

Mechanism of action

Calcitonin gene-related peptide type 1 receptor antagonist

Primary target: Calcitonin gene-related peptide type 1 receptor

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. atogepant Nervous system (N02)
  2. erenumab-aooe Calcitonin gene-related peptide type 1 receptor antagonist
  3. rimegepant Nervous system (N02)
  4. rimegepant sulfate Calcitonin gene-related peptide type 1 receptor antagonist
  5. ubrogepant Calcitonin gene-related peptide type 1 receptor antagonist
  6. erenumab Nervous system (N02)

Frequently asked questions

What is zavegepant hydrochloride?

zavegepant hydrochloride (ZAVZPRET) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: nasal. Current US regulatory status: approved.

What is the brand name for zavegepant hydrochloride?

ZAVZPRET is a marketed brand name for zavegepant hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of zavegepant hydrochloride?

zavegepant hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.