Wednesday, July 8, 2026

Drug profile · INN

rimegepant

rimegepant (VYDURA) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved Nervous system (N02) N02CD06
US status approved
Patents linked 0
Pipeline programs 10
News articles 0
Drug details — rimegepant
US status
approved
Class
Nervous system (N02)
Route
ORAL
Patents
0
Programs
10
Data quality
0.84

Quick answer

rimegepant (VYDURA) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN rimegepant
Brand VYDURA
Mechanism Calcitonin gene-related peptide type 1 receptor antagonist
Target Calcitonin gene-related peptide type 1 receptor
Therapeutic class Nervous system (N02)
Route ORAL
Formulation TABLET, ORALLY DISINTEGRATING
ATC code N02CD06

Mechanism of action

Calcitonin gene-related peptide type 1 receptor antagonist

Primary target: Calcitonin gene-related peptide type 1 receptor

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. C4951002 Phase 3 · First Biotech (Australia) · Acute Migraine (with or without aura)
  2. C4951003 Phase 3 · First Biotech (Australia) · Acute Migraine (with or without aura)
  3. C4951009 Phase 3 · First Biotech (Australia) · Migraine (with or without aura)
  4. C4951013 Phase 3 · First Biotech (Australia) · Chronic Migraine
  5. C4951063 Phase 3 · First Biotech (Australia) · Menstrual Migraine
  6. Rimegepant Phase 3 · Pfizer · Migraine
  7. C4951004/BHV3000-406 Approved · First Biotech (Australia) · Migraine attacks with or without aura
  8. C4951012/BHV3000-407 Approved · First Biotech (Australia) · migraine headaches with or without aura

Related & competitor drugs

  1. aripiprazole Nervous system (N05)
  2. brexpiprazole Nervous system (N05)
  3. brivaracetam Nervous system (N03)
  4. bupivacaine Nervous system (N01)
  5. buprenorphine Nervous system (N07)
  6. caffeine citrate Nervous system (N06)

Frequently asked questions

What is rimegepant?

rimegepant (VYDURA) is a calcitonin gene-related peptide type 1 receptor antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for rimegepant?

VYDURA is a marketed brand name for rimegepant. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of rimegepant?

rimegepant has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.