Friday, July 10, 2026

Drug profile · INN

velaglucerase alfa

velaglucerase alfa (VPRIV) is a glucocerebroside hydrolytic enzyme. Associated with Takeda. Route of administration: intravenous. Current US regulatory status: approved.

FDA: approved EMA: approved Alimentary tract and metabolism (A16) A16AB10
US status approved
Patents linked 0
Pipeline programs 7
News articles 1
Drug details — velaglucerase alfa
US status
approved
Class
Alimentary tract and metabolism (A16)
Route
INTRAVENOUS
Patents
0
Programs
7
Data quality
0.89

Quick answer

velaglucerase alfa (VPRIV) is a glucocerebroside hydrolytic enzyme. Associated with Takeda. Route of administration: intravenous. Current US regulatory status: approved.

Key facts

INN velaglucerase alfa
Brand VPRIV
Mechanism Glucocerebroside hydrolytic enzyme
Target Glucocerebroside
Therapeutic class Alimentary tract and metabolism (A16)
Route INTRAVENOUS
Formulation INJECTABLE
ATC code A16AB10
Originator Takeda

Mechanism of action

Glucocerebroside hydrolytic enzyme

Primary target: Glucocerebroside

Approval history

Authority Status Date
FDA approved
EMA approved

Recent coverage

Pipeline programs

  1. GA-GCB (velaglucerase alfa) Phase 3 · Takeda · Gaucher Disease
  2. VPRIV ®, Phase 3 · Takeda · Gaucher Disease, Type 1
  3. velaglucerase alfa Phase 3 · Shire · Gaucher Disease
  4. velaglucerase alfa Phase 3 · Takeda · Gaucher Disease, Type 1
  5. GA-GCB Phase 2 · Takeda · Gaucher Disease
  6. velaglucerase alfa Phase 2 · Takeda · Gaucher Disease, Type 3
  7. Velaglucerase Alfa Approved · Takeda · Gaucher Disease

Related & competitor drugs

  1. agalsidase alfa Alimentary tract and metabolism (A16)
  2. alogliptin Alimentary tract and metabolism (A10)
  3. alogliptin benzoate Alimentary tract and metabolism (A10)
  4. aprepitant Alimentary tract and metabolism (A04)
  5. budesonide Alimentary tract and metabolism (A07)
  6. canagliflozin Alimentary tract and metabolism (A10)

Frequently asked questions

What is velaglucerase alfa?

velaglucerase alfa (VPRIV) is a glucocerebroside hydrolytic enzyme. Associated with Takeda. Route of administration: intravenous. Current US regulatory status: approved.

What is the brand name for velaglucerase alfa?

VPRIV is a marketed brand name for velaglucerase alfa. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of velaglucerase alfa?

velaglucerase alfa has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.