Friday, July 10, 2026

Drug profile · INN

trazodone hydrochloride

trazodone hydrochloride (TRAZODONE HYDROCHLORIDE) is a serotonin 2a (5-ht2a) receptor antagonist. Associated with Quantum Biopharma. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — trazodone hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
3
Data quality
0.89

Quick answer

trazodone hydrochloride (TRAZODONE HYDROCHLORIDE) is a serotonin 2a (5-ht2a) receptor antagonist. Associated with Quantum Biopharma. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN trazodone hydrochloride
Brand TRAZODONE HYDROCHLORIDE
Mechanism Serotonin 2a (5-HT2a) receptor antagonist
Target 5-hydroxytryptamine receptor 2A
Route ORAL
Formulation TABLET, EXTENDED RELEASE

Mechanism of action

Serotonin 2a (5-HT2a) receptor antagonist

Primary target: 5-hydroxytryptamine receptor 2A

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Trazodone Phase 3 · BRIGHT MINDS BIOSCIENCES · Poor Quality Sleep
  2. 039(C/a)MD23341 Phase 1 · Anaxis Pharma · Intended indication: Major Depressive Disorders with and wit
  3. Trazodone Approved · United Therapeutics Europe · Sleep Apnea

Related & competitor drugs

  1. cyclobenzaprine hydrochloride Serotonin 2c (5-HT2c) receptor antagonist
  2. pimavanserin tartrate Serotonin 2a (5-HT2a) receptor inverse agonist

Frequently asked questions

What is trazodone hydrochloride?

trazodone hydrochloride (TRAZODONE HYDROCHLORIDE) is a serotonin 2a (5-ht2a) receptor antagonist. Associated with Quantum Biopharma. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for trazodone hydrochloride?

TRAZODONE HYDROCHLORIDE is a marketed brand name for trazodone hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of trazodone hydrochloride?

trazodone hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.