Wednesday, July 8, 2026

Drug profile · INN

trabectedin

trabectedin (YONDELIS) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01CX01
US status approved
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — trabectedin
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
INJECTION
Patents
0
Programs
5
Data quality
0.84

Quick answer

trabectedin (YONDELIS) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN trabectedin
Brand YONDELIS
Mechanism DNA inhibitor
Target DNA
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INJECTION
Formulation POWDER
ATC code L01CX01

Mechanism of action

DNA inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved
NMPA clinical trials

Pipeline programs

  1. IT-03 Phase 3 · INTENSITY THERAPEUTICS · liposarcoma (dedifferentiated, myxoid, round cell or pleomor
  2. Trabectedin Phase 3 · Janssen Research & · Ovarian Cancer
  3. REPRAB - MITO 36 Phase 2 · Telethon Foundation · recurrent ovarian cancer
  4. UC-IMM-2302 Phase 2 · Ningbo Cancer Hospital · Patients with dMMR/MSI (non-colorectal/non-endometrial) loca
  5. UC-SAR-2212_L-UteCIN Phase 2 · Ningbo Cancer Hospital · Localized, resected, FIGO stage I (2018 classification), ute

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  3. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  4. anagrelide Antineoplastic and immunomodulating agents (L01)
  5. apremilast Antineoplastic and immunomodulating agents (L04)
  6. arsenic trioxide Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is trabectedin?

trabectedin (YONDELIS) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for trabectedin?

YONDELIS is a marketed brand name for trabectedin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of trabectedin?

trabectedin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.