Wednesday, July 8, 2026

Drug profile · INN

teprotumumab-trbw

teprotumumab-trbw (TEPEZZA) is a insulin-like growth factor i receptor antagonist. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — teprotumumab-trbw
US status
approved
Class
Route
INJECTION
Patents
0
Programs
0
Data quality
0.84

Quick answer

teprotumumab-trbw (TEPEZZA) is a insulin-like growth factor i receptor antagonist. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN teprotumumab-trbw
Brand TEPEZZA
Mechanism Insulin-like growth factor I receptor antagonist
Target Insulin-like growth factor 1 receptor
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Insulin-like growth factor I receptor antagonist

Primary target: Insulin-like growth factor 1 receptor

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. mecasermin Systemic hormonal preparations (H01)
  2. masoprocol Insulin-like growth factor I receptor inhibitor
  3. mecasermin recombinant Insulin-like growth factor I receptor agonist
  4. mecasermin rinfabate recombinant Insulin-like growth factor I receptor agonist
  5. mecasermin rinfabate Insulin-like growth factor I receptor agonist
  6. teprotumumab Antineoplastic and immunomodulating agents (L04)

Frequently asked questions

What is teprotumumab-trbw?

teprotumumab-trbw (TEPEZZA) is a insulin-like growth factor i receptor antagonist. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for teprotumumab-trbw?

TEPEZZA is a marketed brand name for teprotumumab-trbw. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of teprotumumab-trbw?

teprotumumab-trbw has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.