Drug profile · INN
talazoparib tosylate
TALZENNA
talazoparib tosylate (TALZENNA) is a poly [adp-ribose] polymerase-1 inhibitor. Route of administration: oral. Current US regulatory status: approved.
Drug details — talazoparib tosylate
- US status
- approved
- Class
- —
- Route
- ORAL
- Patents
- 3
- Programs
- 2
- Data quality
- 0.84
Quick answer
talazoparib tosylate (TALZENNA) is a poly [adp-ribose] polymerase-1 inhibitor. Route of administration: oral. Current US regulatory status: approved.
Key facts
Mechanism of action
Poly [ADP-ribose] polymerase-1 inhibitor
Primary target: Poly [ADP-ribose] polymerase 2
Approval history
| Authority | Status | Date |
|---|---|---|
| FDA | approved | — |
Recent coverage
Pfizer sharpens prostate cancer case with Talzenna win — oncology
Pfizer announced a Phase III win for Talzenna (talazoparib) plus Xtandi (enzalutamide) in metastatic castration-sensitive prostate cancer, setting up a potential broader label. This analysis covers the TALAPRO-3 results, implications for the prostate cancer treatment landscape, and key milestones for pharma teams and investors.
Pfizer's Talzenna Combo: A Game Changer in Prostate Cancer Treatment
Pfizer has made significant strides with its Talzenna combination therapy for castration-sensitive prostate cancer, surpassing Johnson & Johnson. This article delves into the implications of this breakthrough for the pharmaceutical landscape.
Pipeline programs
Related & competitor drugs
Related patents
-
US 8735392
Crystalline (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt
granted -
US 8420650
Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
granted -
US 8012976
Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
granted
Frequently asked questions
What is talazoparib tosylate?
talazoparib tosylate (TALZENNA) is a poly [adp-ribose] polymerase-1 inhibitor. Route of administration: oral. Current US regulatory status: approved.
What is the brand name for talazoparib tosylate?
TALZENNA is a marketed brand name for talazoparib tosylate. Check FDA Drugs@FDA for the current US label holder and prescribing information.
What is the US approval status of talazoparib tosylate?
talazoparib tosylate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.