Friday, July 10, 2026

Drug profile · INN

talazoparib

talazoparib (TALZENNA) is a poly [adp-ribose] polymerase 2 inhibitor. Associated with Pfizer Australia Pty Ltd.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01XK04
Patents linked 2
Pipeline programs 8
News articles 2
Drug details — talazoparib

Quick answer

talazoparib (TALZENNA) is a poly [adp-ribose] polymerase 2 inhibitor. Associated with Pfizer Australia Pty Ltd.

Key facts

INN talazoparib
Brand TALZENNA
Mechanism Poly [ADP-ribose] polymerase 2 inhibitor
Target Poly [ADP-ribose] polymerase 2
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XK04

Mechanism of action

Poly [ADP-ribose] polymerase 2 inhibitor

Primary target: Poly [ADP-ribose] polymerase 2

Approval history

Authority Status Date
EMA approved
TGA approved

Recent coverage

Pipeline programs

  1. B9991046 Phase 3 · First Biotech (Australia) · Cancer
  2. C3441021 Phase 3 · First Biotech (Australia) · Metastatic Castration-resistant Prostate Cancer
  3. C3441052 Phase 3 · First Biotech (Australia) · Metastatic Castration-sensitive Prostate Cancer
  4. Chemotherapy + avelumab followed by avelumab + talazoparib Phase 3 · Pfizer · Ovarian Cancer
  5. talazoparib plus enzalutamide Phase 3 · Pfizer · Prostate Cancer
  6. Talazoparib Tosylate Phase 2 · BioMarin Pharmaceutical Australia · Advanced Breast Cancer
  7. Talazoparib Phase 1 · BioMarin Pharmaceutical Australia · Childhood Solid Tumors
  8. Talzenna 1 mg hard capsules Approved · Disc Medicine · Breast cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. WO 2026078615

    ASSOCIATION DE TALAZOPARIB ET D'ENZALUTAMIDE DANS LE TRAITEMENT DU CANCER DE LA PROSTATE MÉTASTATIQUE RÉSISTANT À LA CASTRATION

    Expires Wed Apr 11 2046 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. WO 2026078619

    ASSOCIATION DE TALAZOPARIB ET D'ENZALUTAMIDE DANS LE TRAITEMENT DU CANCER DE LA PROSTATE MÉTASTATIQUE RÉSISTANT À LA CASTRATION

    Expires Wed Apr 11 2046 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is talazoparib?

talazoparib (TALZENNA) is a poly [adp-ribose] polymerase 2 inhibitor. Associated with Pfizer Australia Pty Ltd.

What is the brand name for talazoparib?

TALZENNA is a marketed brand name for talazoparib. Check FDA Drugs@FDA for the current US label holder and prescribing information.