Wednesday, July 8, 2026

Drug profile · INN

sulfasalazine

sulfasalazine (PYRALIN EN) is a arachidonate 5-lipoxygenase inhibitor. Associated with Pfizer Australia Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — sulfasalazine
US status
approved
Class
Route
ORAL
Patents
0
Programs
6
Data quality
0.84

Quick answer

sulfasalazine (PYRALIN EN) is a arachidonate 5-lipoxygenase inhibitor. Associated with Pfizer Australia Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN sulfasalazine
Brand PYRALIN EN
Mechanism Arachidonate 5-lipoxygenase inhibitor
Target Polyunsaturated fatty acid 5-lipoxygenase
Route ORAL
Formulation TABLET, DELAYED RELEASE

Mechanism of action

Arachidonate 5-lipoxygenase inhibitor

Primary target: Polyunsaturated fatty acid 5-lipoxygenase

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. M14-671 Phase 3 · AbbVie Deutschland GmbH · Crohn's Disease (CD)
  2. APHP211176 Phase 2 · PARItec · Recently diagnosed non favorable Acute Myeloid Leukemias
  3. Sulfasalazine Phase 1 · Lakefront Biotherapeutics NV · Healthy
  4. Methotrexate plus sulfasalazine Approved · Hospital Authority · Rheumatoid Arthritis
  5. NORD-STAR Approved · George Institute for · Rheumatoid Arthritis
  6. PRIMERA001 Approved · Disc Medicine · Rheumatoid arthritis according to 2010 criteria

Related & competitor drugs

  1. meclofenamate sodium Arachidonate 5-lipoxygenase inhibitor
  2. mesalamine Arachidonate 5-lipoxygenase inhibitor
  3. zileuton Arachidonate 5-lipoxygenase inhibitor
  4. balsalazide disodium Cyclooxygenase inhibitor
  5. olsalazine sodium Arachidonate 5-lipoxygenase inhibitor
  6. mesalazine Arachidonate 5-lipoxygenase inhibitor

Frequently asked questions

What is sulfasalazine?

sulfasalazine (PYRALIN EN) is a arachidonate 5-lipoxygenase inhibitor. Associated with Pfizer Australia Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for sulfasalazine?

PYRALIN EN is a marketed brand name for sulfasalazine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sulfasalazine?

sulfasalazine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.