Drug profile · INN
sotorasib
LUMYKRAS
sotorasib (LUMYKRAS) is a gtpase kras inhibitor. Route of administration: oral. Current US regulatory status: approved.
Drug details — sotorasib
- US status
- approved
- Class
- Antineoplastic and immunomodulating agents (L01)
- Route
- ORAL
- Patents
- 0
- Programs
- 14
- Data quality
- 0.84
Quick answer
sotorasib (LUMYKRAS) is a gtpase kras inhibitor. Route of administration: oral. Current US regulatory status: approved.
Key facts
Mechanism of action
GTPase KRas inhibitor
Primary target: GTPase KRas
Approval history
| Authority | Status | Date |
|---|---|---|
| FDA | approved | — |
| EMA | approved | — |
Recent coverage
5 Notable Oncology FDA Approvals Granted in May: A B2B Analysis
In May 2026, the FDA granted five major oncology approvals, including a first-in-class combination for non-muscle invasive bladder cancer. This analysis covers the approvals, their competitive impact, and next milestones for pharma teams.
KRAS G12C Inhibitors NSCLC: Market Analysis of Sotorasib & Adagrasib
This article delves into the market dynamics of KRAS G12C inhibitors, Sotorasib and Adagrasib, highlighting their roles in non-small cell lung cancer treatment.
FDA Approval KRAS G12C NSCLC: Sotorasib & Adagrasib Insights
Explore the latest insights on FDA-approved Sotorasib and Adagrasib for treating KRAS G12C NSCLC, transforming lung cancer therapy.
FDA Accelerated Approval of KRAS G12C Inhibitors in NSCLC: Sotorasib vs Adagrasib
This article delves into the FDA's accelerated approval of KRAS G12C inhibitors, Sotorasib and Adagrasib, highlighting their impact on NSCLC treatment.
Congress & event coverage
- PresentationASCO 2026
Pipeline programs
Related & competitor drugs
Frequently asked questions
What is sotorasib?
sotorasib (LUMYKRAS) is a gtpase kras inhibitor. Route of administration: oral. Current US regulatory status: approved.
What is the brand name for sotorasib?
LUMYKRAS is a marketed brand name for sotorasib. Check FDA Drugs@FDA for the current US label holder and prescribing information.
What is the US approval status of sotorasib?
sotorasib has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.