Friday, July 10, 2026

Drug profile · INN

serplulimab

serplulimab (HETRONIFLY) is a programmed cell death protein 1 antagonist.

EMA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01FF12
Patents linked 1
Pipeline programs 8
News articles 1
Drug details — serplulimab
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
1
Programs
8
Data quality
0.83

Quick answer

serplulimab (HETRONIFLY) is a programmed cell death protein 1 antagonist.

Key facts

INN serplulimab
Brand HETRONIFLY
Mechanism Programmed cell death protein 1 antagonist
Target Programmed cell death protein 1
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FF12

Mechanism of action

Programmed cell death protein 1 antagonist

Primary target: Programmed cell death protein 1

Approval history

Authority Status Date
EMA approved
NMPA clinical trials

Recent coverage

Pipeline programs

  1. Anti-PD-1 antibody drug named Serplulimab Phase 3 · Chinese Academy of · Locally Advanced Rectal Cancer (LARC)
  2. serplulimab、bevacizumab Phase 3 · Changhai Hospital · Rectal Cancer
  3. Serplulimab Phase 2 · First People's Hospital · Gastric Cancer
  4. Serplulimab Phase 2 · First People's Hospital · HER2-positive Gastric Cancer
  5. Serplulimab Phase 2 · First People's Hospital · Colorectal Cancer (Diagnosis)
  6. Surufatinib + Serplulimab+Albumin-paclitaxel + Gemcitabine Phase 2 · Sun Yat-sen University · Locally Advanced Pancreatic Cancer
  7. megestrol acetate oral suspension + serplulimab + SOX Phase 2 · First People's Hospital · Stage III Gastric Cancer
  8. ES-2024-072-02 Unknown · First People's Hospital · Small Cell Lung Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Related patents

  1. NO 2026007

    Serplulimab

    Expires Wed Jan 17 2046 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is serplulimab?

serplulimab (HETRONIFLY) is a programmed cell death protein 1 antagonist.

What is the brand name for serplulimab?

HETRONIFLY is a marketed brand name for serplulimab. Check FDA Drugs@FDA for the current US label holder and prescribing information.