Wednesday, July 8, 2026

Drug profile · INN

toripalimab-tpzi

toripalimab-tpzi (LOQTORZI) is a programmed cell death protein 1 antagonist. Associated with Coherus Oncology. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 3
Pipeline programs 20
News articles 0
Drug details — toripalimab-tpzi
US status
approved
Class
Route
INJECTION
Patents
3
Programs
20
Data quality
0.89

Quick answer

toripalimab-tpzi (LOQTORZI) is a programmed cell death protein 1 antagonist. Associated with Coherus Oncology. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN toripalimab-tpzi
Brand LOQTORZI
Mechanism Programmed cell death protein 1 antagonist
Target Programmed cell death protein 1
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Programmed cell death protein 1 antagonist

Primary target: Programmed cell death protein 1

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Toripalimab Phase 3 · Chinese Academy of · Non Small Cell Lung Cancer
  2. Toripalimab Phase 3 · Chinese Academy of · Nasopharyngeal Carcinoma
  3. toripalimab Phase 3 · Chinese Academy of · Esophageal Cancer
  4. Toripalimab Phase 2 · Chinese Academy of · Neoadjuvant Therapy
  5. Toripalimab Phase 2 · First People's Hospital · Breast Cancer
  6. Toripalimab Phase 2 · First People's Hospital · Locally Advanced Colon Cancer
  7. Toripalimab Phase 2 · Chinese Academy of · Triple-Negative Breast Cancer (TNBC)
  8. Toripalimab Phase 2 · First People's Hospital · Urinary Bladder Neoplasms

Related & competitor drugs

  1. cemiplimab Antineoplastic and immunomodulating agents (L01)
  2. cemiplimab-rwlc Programmed cell death protein 1 inhibitor
  3. tislelizumab Antineoplastic and immunomodulating agents (L01)
  4. dostarlimab-gxly Programmed cell death protein 1 antagonist
  5. islelizumab-jsgr Programmed cell death protein 1 inhibitor
  6. nivolumab Antineoplastic and immunomodulating agents (L01)
  1. US 11583584

    Stable protein compositions and methods of their use

    Expires Mon Feb 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11576971

    Method of filling a container with no headspace

    Expires Mon Feb 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11071782

    Method of filling a container with no headspace

    Expires Mon Jul 22 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is toripalimab-tpzi?

toripalimab-tpzi (LOQTORZI) is a programmed cell death protein 1 antagonist. Associated with Coherus Oncology. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for toripalimab-tpzi?

LOQTORZI is a marketed brand name for toripalimab-tpzi. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of toripalimab-tpzi?

toripalimab-tpzi has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.