Wednesday, July 8, 2026

Drug profile · INN

ranolazine

ranolazine (RANEXA (PREVIOUSLY LATIXA)) is a sodium channel protein type iv alpha subunit blocker. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved Cardiovascular system (C01) C01EB18
US status approved
Patents linked 0
Pipeline programs 20
News articles 0
Drug details — ranolazine
US status
approved
Class
Cardiovascular system (C01)
Route
ORAL
Patents
0
Programs
20
Data quality
0.89

Quick answer

ranolazine (RANEXA (PREVIOUSLY LATIXA)) is a sodium channel protein type iv alpha subunit blocker. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN ranolazine
Brand RANEXA (PREVIOUSLY LATIXA)
Mechanism Sodium channel protein type IV alpha subunit blocker
Target Sodium channel protein type 4 subunit alpha
Therapeutic class Cardiovascular system (C01)
Route ORAL
Formulation GRANULE, EXTENDED RELEASE
ATC code C01EB18

Mechanism of action

Sodium channel protein type IV alpha subunit blocker

Primary target: Sodium channel protein type 4 subunit alpha

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. APHP200043 Phase 3 · PARItec · Hemoptysis, whatever the cause, with the exception of cystic
  2. D9604C00001 Phase 3 · AstraZeneca · Reversal of anticoagulation effect in patients on a FXa inhi
  3. RANOLAZINE, FLECARDIA Διάλυμα για ένεση/έχχυση Phase 3 · Anaxis Pharma · Restoration of sinus rhythm in patients with recent AF onset
  4. Tranexamic Acid Phase 3 · Arrowhead Pharmaceuticals Ireland · Hemorrhagic Shock
  5. Tranexamic Acid Phase 3 · United Therapeutics Europe · Spinal Injuries
  6. Tranexamic acid Phase 3 · First People's Hospital · Hemorrhage, Postpartum
  7. pad-gauze with tranexamic acid (Hemostopan™) Phase 3 · Sionna Therapeutics · Bleeding
  8. Tranexamic Acid Phase 2 · United Therapeutics Europe · Hemorrhage

Related & competitor drugs

  1. alirocumab Cardiovascular system (C10)
  2. aliskiren Cardiovascular system (C09)
  3. azilsartan medoxomil Cardiovascular system (C09)
  4. bempedoic acid Cardiovascular system (C10)
  5. bosentan Cardiovascular system (C02)
  6. bupivacaine Nervous system (N01)

Frequently asked questions

What is ranolazine?

ranolazine (RANEXA (PREVIOUSLY LATIXA)) is a sodium channel protein type iv alpha subunit blocker. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for ranolazine?

RANEXA (PREVIOUSLY LATIXA) is a marketed brand name for ranolazine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ranolazine?

ranolazine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.