Wednesday, July 8, 2026

Drug profile · INN

ramucirumab

ramucirumab (CYRAMZA) is a vascular endothelial growth factor receptor 2 inhibitor. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved PMDA: approved Antineoplastic and immunomodulating agents (L01) L01FX06
US status approved
Patents linked 0
Pipeline programs 14
News articles 1
Drug details — ramucirumab
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
INJECTION
Patents
0
Programs
14
Data quality
0.84

Quick answer

ramucirumab (CYRAMZA) is a vascular endothelial growth factor receptor 2 inhibitor. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ramucirumab
Brand CYRAMZA
Mechanism Vascular endothelial growth factor receptor 2 inhibitor
Target Vascular endothelial growth factor receptor 2
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INJECTION
Formulation INJECTABLE
ATC code L01FX06

Mechanism of action

Vascular endothelial growth factor receptor 2 inhibitor

Primary target: Vascular endothelial growth factor receptor 2

Approval history

Authority Status Date
FDA approved
EMA approved
PMDA approved

Recent coverage

Pipeline programs

  1. AT148006 Phase 3 · Createrna Science and · Patients with HER2-overexpressing advanced or metastatic gas
  2. D9802C00001 Phase 3 · AstraZeneca · Gastric cancer, Advanced/Metastatic Gastric cancer, Gastroes
  3. DS8201-A-U306 Phase 3 · Daiichi Sankyo US · Metastatic Gastric Adenocarcinoma
  4. RAMIRIS Phase 3 · George Institute for · advanced or metastatic adenocarcinoma of the stomach or gast
  5. RAMUCIRUMAB, ERLOTINIB Phase 3 · Eli Lilly and · Metastatic Non-Small Cell Lung Cancer
  6. Ramucirumab Phase 3 · Eli Lilly and · Urothelial Carcinoma
  7. ramucirumab Phase 3 · Eli Lilly and · Gastric Cancer
  8. Cyramza /ml concentrate for stomach cancer stage IV with me… Phase 2 · CERo Therapeutics · stomach cancer stage IV with metastases

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is ramucirumab?

ramucirumab (CYRAMZA) is a vascular endothelial growth factor receptor 2 inhibitor. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ramucirumab?

CYRAMZA is a marketed brand name for ramucirumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ramucirumab?

ramucirumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.