Wednesday, July 8, 2026

Drug profile · INN

plerixafor

plerixafor (PLERIXAFOR ARX) is a c-x-c chemokine receptor type 4 partial agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: subcutaneous. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L03) L03AX16
US status approved
Patents linked 20
Pipeline programs 15
News articles 0
Drug details — plerixafor
US status
approved
Class
Antineoplastic and immunomodulating agents (L03)
Route
SUBCUTANEOUS
Patents
20
Programs
15
Data quality
0.89

Quick answer

plerixafor (PLERIXAFOR ARX) is a c-x-c chemokine receptor type 4 partial agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: subcutaneous. Current US regulatory status: approved.

Key facts

INN plerixafor
Brand PLERIXAFOR ARX
Mechanism C-X-C chemokine receptor type 4 partial agonist
Target C-X-C chemokine receptor type 4
Therapeutic class Antineoplastic and immunomodulating agents (L03)
Route SUBCUTANEOUS
Formulation SOLUTION
ATC code L03AX16

Mechanism of action

C-X-C chemokine receptor type 4 partial agonist

Primary target: C-X-C chemokine receptor type 4

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved

Pipeline programs

  1. CTX001-111 Phase 3 · Vertex Pharmaceuticals (Australia) · Transfusion-dependent β-thalassemia (TDT)
  2. OTL-103-4 Phase 3 · Telethon Foundation · Wiskott-Aldrich Syndrome
  3. OTL-203-02 Phase 3 · ORCHARD THERAPEUTICS · Mucopolysaccharidosis type I, Hurler Syndrome
  4. VX21-CTX001-141 Phase 3 · Vertex Pharmaceuticals (Australia) · Transfusion-Dependent-Thalassemia
  5. VX21-CTX001-151 Phase 3 · Vertex Pharmaceuticals (Australia) · Severe sickle cell disease (SCD)
  6. VX21-CTX001-161 Phase 3 · Vertex Pharmaceuticals (Australia) · Transfusion-dependent β-thalassemia (TDT), Severe sickle cel
  7. Busulfan Koanaa /ml Konzentrat zur Herstellun... Phase 2 · Telethon Foundation · transfusion-dependent beta-thalassemia
  8. CTX001-121 Phase 2 · Vertex Pharmaceuticals (Australia) · Severe sickle cell disease (SCD)

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
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Frequently asked questions

What is plerixafor?

plerixafor (PLERIXAFOR ARX) is a c-x-c chemokine receptor type 4 partial agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: subcutaneous. Current US regulatory status: approved.

What is the brand name for plerixafor?

PLERIXAFOR ARX is a marketed brand name for plerixafor. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of plerixafor?

plerixafor has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.