Wednesday, July 8, 2026

Drug profile · INN

pegaspargase

pegaspargase (ONCASPAR) is a asparagine hydrolytic enzyme. Current US regulatory status: approved.

FDA: approved EMA: approved Antineoplastic and immunomodulating agents (L01) L01XX24
US status approved
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — pegaspargase
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
5
Data quality
0.83

Quick answer

pegaspargase (ONCASPAR) is a asparagine hydrolytic enzyme. Current US regulatory status: approved.

Key facts

INN pegaspargase
Brand ONCASPAR
Mechanism Asparagine hydrolytic enzyme
Target Asparagine
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Formulation VIAL
ATC code L01XX24

Mechanism of action

Asparagine hydrolytic enzyme

Primary target: Asparagine

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. 20190360 Phase 3 · Amgen · Newly diagnosed Philadelphia-negative B-cell precursor Acute
  2. PEGASPARGASE Phase 3 · PARItec · This is a prospective, French, multicenter, open-label, desi
  3. 2023-SR-002 Phase 2 · First People's Hospital · NK-T-Cell Lymphoma, Extranodal
  4. ALL3024 Phase 2 · Telethon Foundation · Very High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL)
  5. B1931036 Phase 2 · First Biotech (Australia) · Acute Lymphoblastic Leukemia (ALL)

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. asparaginase erwinia chrysanthemi (recombinant)-rywn Asparagine hydrolytic enzyme
  6. axitinib Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is pegaspargase?

pegaspargase (ONCASPAR) is a asparagine hydrolytic enzyme. Current US regulatory status: approved.

What is the brand name for pegaspargase?

ONCASPAR is a marketed brand name for pegaspargase. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of pegaspargase?

pegaspargase has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.