Wednesday, July 8, 2026

Drug profile · INN

pegaptanib sodium

pegaptanib sodium (MACUGEN) is a vascular endothelial growth factor a antagonist. Route of administration: intravitreal. Current US regulatory status: approved.

FDA: approved PMDA: approved
US status approved
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — pegaptanib sodium
US status
approved
Class
Route
INTRAVITREAL
Patents
0
Programs
1
Data quality
0.84

Quick answer

pegaptanib sodium (MACUGEN) is a vascular endothelial growth factor a antagonist. Route of administration: intravitreal. Current US regulatory status: approved.

Key facts

INN pegaptanib sodium
Brand MACUGEN
Mechanism Vascular endothelial growth factor A antagonist
Target Vascular endothelial growth factor A, long form
Route INTRAVITREAL
Formulation INJECTABLE

Mechanism of action

Vascular endothelial growth factor A antagonist

Primary target: Vascular endothelial growth factor A, long form

Approval history

Authority Status Date
FDA approved
PMDA approved

Pipeline programs

  1. pegaptanib sodium Phase 3 · Pfizer · Macular Degeneration

Related & competitor drugs

  1. bevacizumab Antineoplastic and immunomodulating agents (L01)
  2. bevacizumab-maly Vascular endothelial growth factor A inhibitor
  3. bevacizumab-adcd Vascular endothelial growth factor A inhibitor
  4. bevacizumab-awwb Vascular endothelial growth factor A inhibitor
  5. bevacizumab-bvzr Vascular endothelial growth factor A inhibitor
  6. bevacizumab-tnjn Vascular endothelial growth factor A inhibitor

Frequently asked questions

What is pegaptanib sodium?

pegaptanib sodium (MACUGEN) is a vascular endothelial growth factor a antagonist. Route of administration: intravitreal. Current US regulatory status: approved.

What is the brand name for pegaptanib sodium?

MACUGEN is a marketed brand name for pegaptanib sodium. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of pegaptanib sodium?

pegaptanib sodium has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.