Wednesday, July 8, 2026

Drug profile · INN

palovarotene

palovarotene (SOHONOS) is a retinoic acid receptor gamma agonist. Associated with Ipsen. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: refused TGA: approved Musculo-skeletal system (M09) M09AX11
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — palovarotene
US status
approved
Class
Musculo-skeletal system (M09)
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

palovarotene (SOHONOS) is a retinoic acid receptor gamma agonist. Associated with Ipsen. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN palovarotene
Brand SOHONOS
Mechanism Retinoic acid receptor gamma agonist
Target Retinoic acid receptor gamma
Therapeutic class Musculo-skeletal system (M09)
Route ORAL
Formulation CAPSULE
ATC code M09AX11
Originator Ipsen

Mechanism of action

Retinoic acid receptor gamma agonist

Primary target: Retinoic acid receptor gamma

Approval history

Authority Status Date
FDA approved
EMA refused
TGA approved

Related & competitor drugs

  1. allopurinol Musculo-skeletal system (M04)
  2. colchicine Musculo-skeletal system (M04)
  3. denosumab Musculo-skeletal system (M05)
  4. eteplirsen Musculo-skeletal system (M09)
  5. febuxostat Musculo-skeletal system (M04)
  6. ibandronic acid Musculo-skeletal system (M05)

Frequently asked questions

What is palovarotene?

palovarotene (SOHONOS) is a retinoic acid receptor gamma agonist. Associated with Ipsen. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for palovarotene?

SOHONOS is a marketed brand name for palovarotene. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of palovarotene?

palovarotene has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.