Wednesday, July 8, 2026

Drug profile · INN

osilodrostat phosphate

osilodrostat phosphate (ISTURISA) is a cytochrome p450 11b1 inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — osilodrostat phosphate
US status
approved
Class
Route
ORAL
Patents
0
Programs
2
Data quality
0.84

Quick answer

osilodrostat phosphate (ISTURISA) is a cytochrome p450 11b1 inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN osilodrostat phosphate
Brand ISTURISA
Mechanism Cytochrome P450 11B1 inhibitor
Target Cytochrome P450 11B1, mitochondrial
Route ORAL
Formulation TABLET

Mechanism of action

Cytochrome P450 11B1 inhibitor

Primary target: Cytochrome P450 11B1, mitochondrial

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. CLCI699C2203 Phase 2 · Recordati Ireland · Cushing's disease
  2. Osilodrostat (Isturisa) Approved · Ultragenyx UK · Mild Autonomous Cortisol Secretion (MACS)

Related & competitor drugs

  1. metyrapone Cytochrome P450 11B1, mitochondrial inhibitor

Frequently asked questions

What is osilodrostat phosphate?

osilodrostat phosphate (ISTURISA) is a cytochrome p450 11b1 inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for osilodrostat phosphate?

ISTURISA is a marketed brand name for osilodrostat phosphate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of osilodrostat phosphate?

osilodrostat phosphate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.