Wednesday, July 8, 2026

Drug profile · INN

ocriplasmin

ocriplasmin (JETREA) is a laminin hydrolytic enzyme. Route of administration: intravitreal. Current US regulatory status: approved.

FDA: approved EMA: withdrawn Sensory organs (S01) S01XA22
US status approved
Patents linked 0
Pipeline programs 0
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Drug details — ocriplasmin
US status
approved
Class
Sensory organs (S01)
Route
INTRAVITREAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

ocriplasmin (JETREA) is a laminin hydrolytic enzyme. Route of administration: intravitreal. Current US regulatory status: approved.

Key facts

INN ocriplasmin
Brand JETREA
Mechanism Laminin hydrolytic enzyme
Target Collagen
Therapeutic class Sensory organs (S01)
Route INTRAVITREAL
Formulation INJECTABLE
ATC code S01XA22

Mechanism of action

Laminin hydrolytic enzyme

Primary target: Collagen

Approval history

Authority Status Date
FDA approved
EMA withdrawn

Related & competitor drugs

  1. aflibercept Sensory organs (S01)
  2. atropine sulfate Sensory organs (S01)
  3. beremagene geperpavec Dermatologicals (D03)
  4. bimatoprost Sensory organs (S01)
  5. atropine Sensory organs (S01)
  6. brinzolamide Sensory organs (S01)

Frequently asked questions

What is ocriplasmin?

ocriplasmin (JETREA) is a laminin hydrolytic enzyme. Route of administration: intravitreal. Current US regulatory status: approved.

What is the brand name for ocriplasmin?

JETREA is a marketed brand name for ocriplasmin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ocriplasmin?

ocriplasmin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.