Friday, July 10, 2026

Drug profile · INN

niraparib tosilate hydrate

niraparib tosilate hydrate (ZEJULA) is a poly [adp-ribose] polymerase 2 inhibitor.

PMDA: approved
Patents linked 0
Pipeline programs 8
News articles 0
Drug details — niraparib tosilate hydrate
Class
Route
Patents
0
Programs
8
Data quality
0.78

Quick answer

niraparib tosilate hydrate (ZEJULA) is a poly [adp-ribose] polymerase 2 inhibitor.

Key facts

INN niraparib tosilate hydrate
Brand ZEJULA
Mechanism Poly [ADP-ribose] polymerase 2 inhibitor
Target Poly [ADP-ribose] polymerase 2

Mechanism of action

Poly [ADP-ribose] polymerase 2 inhibitor

Primary target: Poly [ADP-ribose] polymerase 2

Approval history

Authority Status Date
PMDA approved

Pipeline programs

  1. IMFINZI for Advanced Biliary Cancer (ABC) Phase 3 · Ningbo Cancer Hospital · Advanced Biliary Cancer (ABC)
  2. 2020/3093 NIRADO Phase 2 · George Institute for · DNA repair-deficient or platinum-sensitive solid tumors
  3. 213357 Phase 2 · TESARO Bio Netherlands · Ovarian Neoplasms
  4. 219590 Phase 2 · GSK Glaxo Smith · Neoplasms
  5. GINECO-EN203b Phase 2 · Ningbo Cancer Hospital · metastatic or recurrent endometrial or ovarian carcinosarcom
  6. JEMPERLI for HPV-negative Head and Neck Squa… Phase 2 · Telethon Foundation · HPV-negative Head and Neck Squamous Cell Carcinoma (HNSCC)
  7. MS201924_0002 Phase 2 · MSD Merck Sharp · Epithelial ovarian cancer that progressed on prior PARP inhi
  8. 213406 Phase 1 · GSK Glaxo Smith · Solid Tumours

Related & competitor drugs

  1. niraparib tosylate Poly [ADP-ribose] polymerase 2 inhibitor
  2. talazoparib tosylate Poly [ADP-ribose] polymerase-1 inhibitor
  3. niraparib Antineoplastic and immunomodulating agents (L01)
  4. talazoparib Antineoplastic and immunomodulating agents (L01)
  5. talazoparib tosilate Poly [ADP-ribose] polymerase 2 inhibitor
  6. imp4297 Poly [ADP-ribose] polymerase 2 inhibitor

Frequently asked questions

What is niraparib tosilate hydrate?

niraparib tosilate hydrate (ZEJULA) is a poly [adp-ribose] polymerase 2 inhibitor.

What is the brand name for niraparib tosilate hydrate?

ZEJULA is a marketed brand name for niraparib tosilate hydrate. Check FDA Drugs@FDA for the current US label holder and prescribing information.