Friday, July 10, 2026

Drug profile · INN

niraparib

niraparib (ZEJULA) is a poly [adp-ribose] polymerase-1 inhibitor. Associated with GlaxoSmithKline.

EMA: approved TGA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01
Patents linked 0
Pipeline programs 25
News articles 0
Drug details — niraparib
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
25
Data quality
0.83

Quick answer

niraparib (ZEJULA) is a poly [adp-ribose] polymerase-1 inhibitor. Associated with GlaxoSmithKline.

Key facts

INN niraparib
Brand ZEJULA
Mechanism Poly [ADP-ribose] polymerase-1 inhibitor
Target Poly [ADP-ribose] polymerase 2
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01

Mechanism of action

Poly [ADP-ribose] polymerase-1 inhibitor

Primary target: Poly [ADP-ribose] polymerase 2

Approval history

Authority Status Date
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. 213350/3000-03-005 Phase 3 · TESARO Bio Netherlands · Stage 3 or 4 Non-mucinous Epithelial Ovarian Cancer
  2. 213400 Phase 3 · GSK Glaxo Smith · Lung Cancer, Non-Small Cell
  3. 4010-03-001 Phase 3 · TESARO Bio Netherlands · Recurrent or primary advanced (Stage III or IV) endometrial
  4. 64091742PCR3001 Phase 3 · Janssen-Cilag International N.V · Metastatic Prostate Cancer
  5. 67652000PCR3002 Phase 3 · Janssen-Cilag International N.V · Deleterious Germline or Somatic Homologous Recombination Rep
  6. Glatiramer Acetate (GA) 40 mg Phase 3 · Teva Pharma · Relapsing Remitting Multiple Sclerosis
  7. Glatiramer acetate (GA) Phase 3 · Teva Pharma · Relapsing Remitting Multiple Sclerosis
  8. MITO 33 Phase 3 · Telethon Foundation · Recurrent ovarian, fallopian tube or primary peritoneal canc

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is niraparib?

niraparib (ZEJULA) is a poly [adp-ribose] polymerase-1 inhibitor. Associated with GlaxoSmithKline.

What is the brand name for niraparib?

ZEJULA is a marketed brand name for niraparib. Check FDA Drugs@FDA for the current US label holder and prescribing information.