Drug profile · INN
mitapivat sulfate
PYRUKYND
mitapivat sulfate (PYRUKYND) is a pyruvate kinase isozymes r/l activator. Associated with Agios Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.
Drug details — mitapivat sulfate
- US status
- approved
- Class
- —
- Route
- ORAL
- Patents
- 20
- Programs
- 7
- Data quality
- 0.89
Quick answer
mitapivat sulfate (PYRUKYND) is a pyruvate kinase isozymes r/l activator. Associated with Agios Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.
Key facts
Mechanism of action
Pyruvate kinase isozymes R/L activator
Primary target: Pyruvate kinase PKLR
Approval history
| Authority | Status | Date |
|---|---|---|
| FDA | approved | — |
Pipeline programs
Related & competitor drugs
Related patents
-
US 12428376
Therapeutic compounds and compositions
granted -
US 12133853
Pyruvate kinase activators for use in treating blood disorders
granted -
US 11957680
Pyruvate kinase activators for use in treating blood disorders
granted -
US 11919915
Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations
granted -
US 11878049
Mitapivat therapy and modulators of cytochrome P450
granted -
US 11872225
Pyruvate kinase modulators and use thereof
granted -
US 11866411
Therapeutic compounds and compositions
granted -
US 11793806
Pyruvate kinase activators for use in therapy
granted -
US 11590132
Pyruvate kinase activators for use in treating blood disorders
granted -
US 11464775
Pyruvate kinase modulators and use thereof
granted -
US 11364240
Pyruvate kinase activators for use in treating blood disorders
granted -
US 11254652
Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
granted -
US 11234976
Methods of using pyruvate kinase activators
granted -
US 11040036
Pyruvate kinase activators for use in treating blood disorders
granted -
US 11021515
Therapeutically active compounds and their methods of use
granted -
US 10988448
Therapeutic compounds and compositions
granted -
US 10946023
Therapeutically active compounds and their methods of use
granted -
US 10730854
Therapeutically active compounds and their methods of use
granted -
US 10689375
Compounds and their methods of use
granted -
US 10689414
Therapeutically active compounds and their methods of use
granted
Frequently asked questions
What is mitapivat sulfate?
mitapivat sulfate (PYRUKYND) is a pyruvate kinase isozymes r/l activator. Associated with Agios Netherlands B.V.. Route of administration: oral. Current US regulatory status: approved.
What is the brand name for mitapivat sulfate?
PYRUKYND is a marketed brand name for mitapivat sulfate. Check FDA Drugs@FDA for the current US label holder and prescribing information.
What is the US approval status of mitapivat sulfate?
mitapivat sulfate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.