🇺🇸 FDA
Company

AGIOS

AGIOS PHARMACEUTICALS, INC.

AGIO pharma USA

Quick answer

AGIOS is a pharma company (AGIO) headquartered in CAMBRIDGE, MA, USA with 24 tracked pipeline programs.

Pipeline (24)

project

AG-348

Pyruvate Kinase Deficiency

Phase 3 · small_molecule · completed

2 trials project

Mitapivat

Non-Transfusion-dependent Alpha-Thalassemia

Phase 3 · small_molecule · active

1 trials project

Mitapivat

Pediatric Pyruvate Kinase Deficiency

Phase 3 · small_molecule · active

2 trials project

Mitapivat

Sickle Cell Disease

Phase 3 · small_molecule · active

2 trials project

Mitapivat Matched Placebo

Transfusion-dependent Alpha-Thalassemia

Phase 3 · small_molecule · active

1 trials project

Placebo

Pyruvate Kinase Deficiency

Phase 3 · small_molecule · completed

1 trials project

Placebo Matching Mitapivat

Transfusion-dependent Alpha-Thalassemia

Phase 3 · small_molecule · active

1 trials project

Placebo Matching Mitapivat

Non-Transfusion-dependent Alpha-Thalassemia

Phase 3 · small_molecule · active

1 trials project

AG-120

Chondrosarcoma

Phase 2 · small_molecule · active

1 trials project

AG-348

Thalassemia

Phase 2 · small_molecule · active

1 trials project

Enasidenib

Hematologic Neoplasms

Phase 2 · small_molecule · completed

1 trials project

Mitapivat

Anemia

Phase 2 · small_molecule · active

1 trials project

Tebapivat

Myelodysplastic Syndromes

Phase 2 · small_molecule · active

1 trials project

Tebapivat

Sickle Cell Disease

Phase 2 · small_molecule · active

1 trials project

ivosidenib and nivolumab

Advanced Solid Tumor

Phase 2 · small_molecule · completed

1 trials project

AG-120 (Ivosidenib)

Hepatic Impairment

Phase 1 · small_molecule · completed

1 trials project

AG-181

Phenylketonuria

Phase 1 · small_molecule · active

1 trials project

AG-181

Healthy Volunteers

Phase 1 · small_molecule · completed

1 trials project

AG-236

Healthy Participants

Phase 1 · small_molecule · active

1 trials project

AG-348

Healthy

Phase 1 · small_molecule · completed

1 trials project

AG-348

Sickle Cell Disease

Phase 1 · small_molecule · completed

1 trials project

AG-348

Healthy Volunteers

Phase 1 · small_molecule · completed

1 trials project

AG-348

Healthy Volunteer

Phase 1 · small_molecule · completed

2 trials project

AG-348 Sequence A

Healthy Volunteers

Phase 1 · small_molecule · completed

1 trials

Drugs (1)

drug

mitapivat sulfate

PYRUKYND

Patents (8)

patent

US 12428376

Therapeutic compounds and compositions

Expires Mon Sep 25 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 12377093

Pyruvate kinase activators for use in therapy

Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 12133853

Pyruvate kinase activators for use in treating blood disorders

Expires Mon Oct 31 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 11957680

Pyruvate kinase activators for use in treating blood disorders

Expires Mon Apr 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 11919915

Compounds and methods useful for stabilizing phenylalanine hydroxylase mutations

Expires Mon Feb 29 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 11878049

Mitapivat therapy and modulators of cytochrome P450

Expires Mon Jan 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 11872225

Pyruvate kinase modulators and use thereof

Expires Mon Jan 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

 patent

US 11866411

Therapeutic compounds and compositions

Expires Mon Jan 04 2044 00:00:00 GMT+0000 (Coordinated Universal Time)