Wednesday, July 8, 2026

Drug profile · INN

midodrine hydrochloride

midodrine hydrochloride (ORVATEN) is a adrenergic receptor alpha-1 agonist. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — midodrine hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
3
Data quality
0.89

Quick answer

midodrine hydrochloride (ORVATEN) is a adrenergic receptor alpha-1 agonist. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN midodrine hydrochloride
Brand ORVATEN
Mechanism Adrenergic receptor alpha-1 agonist
Target Adrenergic receptor alpha-1
Route ORAL
Formulation TABLET
Originator Takeda

Mechanism of action

Adrenergic receptor alpha-1 agonist

Primary target: Adrenergic receptor alpha-1

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Midodrine Hydrochloride Approved · Takeda · Hypotension, Orthostatic
  2. midodrine hydrochloride (ProAmatine®) Approved · Takeda · Hypotension, Orthostatic
  3. midodrine Unknown · Ultragenyx UK · Syncope

Related & competitor drugs

  1. carvedilol Adrenergic receptor beta antagonist
  2. doxazosin mesylate Adrenergic receptor alpha-1 antagonist
  3. phenylephrine hydrochloride Adrenergic receptor alpha-1 agonist
  4. prazosin hydrochloride Adrenergic receptor alpha-1 antagonist
  5. tamsulosin hydrochloride Adrenergic receptor alpha-1 antagonist
  6. terazosin hydrochloride Adrenergic receptor alpha-1 antagonist

Frequently asked questions

What is midodrine hydrochloride?

midodrine hydrochloride (ORVATEN) is a adrenergic receptor alpha-1 agonist. Associated with Takeda. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for midodrine hydrochloride?

ORVATEN is a marketed brand name for midodrine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of midodrine hydrochloride?

midodrine hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.