Friday, July 10, 2026

Drug profile · INN

methixene hydrochloride

methixene hydrochloride (TREST) is a muscarinic acetylcholine receptor m1 antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — methixene hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

methixene hydrochloride (TREST) is a muscarinic acetylcholine receptor m1 antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN methixene hydrochloride
Brand TREST
Mechanism Muscarinic acetylcholine receptor M1 antagonist
Target Muscarinic acetylcholine receptor M1
Route ORAL
Formulation TABLET

Mechanism of action

Muscarinic acetylcholine receptor M1 antagonist

Primary target: Muscarinic acetylcholine receptor M1

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. atropine sulfate Sensory organs (S01)
  2. benztropine mesylate Muscarinic acetylcholine receptor M1 antagonist
  3. dicyclomine hydrochloride Muscarinic acetylcholine receptor M3 antagonist
  4. glycopyrrolate Muscarinic acetylcholine receptor M3 antagonist
  5. pilocarpine hydrochloride Muscarinic acetylcholine receptor M3 agonist
  6. scopolamine Muscarinic acetylcholine receptor M1 antagonist

Frequently asked questions

What is methixene hydrochloride?

methixene hydrochloride (TREST) is a muscarinic acetylcholine receptor m1 antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for methixene hydrochloride?

TREST is a marketed brand name for methixene hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of methixene hydrochloride?

methixene hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.