Friday, July 10, 2026

Drug profile · INN

luspatercept-aamt

luspatercept-aamt (REBLOZYL) is a transforming growth factor beta inhibitor. Route of administration: subcutaneous. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — luspatercept-aamt
US status
approved
Class
Route
SUBCUTANEOUS
Patents
0
Programs
6
Data quality
0.84

Quick answer

luspatercept-aamt (REBLOZYL) is a transforming growth factor beta inhibitor. Route of administration: subcutaneous. Current US regulatory status: approved.

Key facts

INN luspatercept-aamt
Brand REBLOZYL
Mechanism Transforming growth factor beta inhibitor
Target Transforming growth factor beta
Route SUBCUTANEOUS
Formulation POWDER

Mechanism of action

Transforming growth factor beta inhibitor

Primary target: Transforming growth factor beta

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. ACE-536-LTFU-001 Phase 3 · Celgene · myelodysplastic syndrome (MDS); beta (β)-thalassemia (THAL);
  2. ACE-536-MF-002 Phase 3 · Celgene · Anemia associated with myeloproliferative neoplasm (MPN)-ass
  3. CA0561060 Phase 3 · Celgene · Myelodysplastic syndrome
  4. Luspatercept Phase 2 · Chinese Academy of · HSCT
  5. Reblozyl 75 mg powder for solution for injection Phase 2 · GSK Glaxo Smith · Myelofibrosis
  6. Luspatercept Unknown · First People's Hospital · Transfusion-dependent Non-severe Aplastic Anemia

Related & competitor drugs

  1. luspatercept Blood and blood forming organs (B03)

Frequently asked questions

What is luspatercept-aamt?

luspatercept-aamt (REBLOZYL) is a transforming growth factor beta inhibitor. Route of administration: subcutaneous. Current US regulatory status: approved.

What is the brand name for luspatercept-aamt?

REBLOZYL is a marketed brand name for luspatercept-aamt. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of luspatercept-aamt?

luspatercept-aamt has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.