Friday, July 10, 2026

Drug profile · INN

lumasiran

lumasiran (OXLUMO) is a hydroxyacid oxidase 1 mrna rnai inhibitor. Associated with Lacuna Pharma Pty Ltd.

EMA: approved TGA: approved Alimentary tract and metabolism (A16) A16AX18
Patents linked 0
Pipeline programs 6
News articles 1
Drug details — lumasiran

Quick answer

lumasiran (OXLUMO) is a hydroxyacid oxidase 1 mrna rnai inhibitor. Associated with Lacuna Pharma Pty Ltd.

Key facts

INN lumasiran
Brand OXLUMO
Mechanism Hydroxyacid oxidase 1 mRNA RNAi inhibitor
Therapeutic class Alimentary tract and metabolism (A16)
ATC code A16AX18

Mechanism of action

Hydroxyacid oxidase 1 mRNA RNAi inhibitor

Approval history

Authority Status Date
EMA approved
TGA approved

Recent coverage

Pipeline programs

  1. Lumasiran Phase 3 · Alnylam Netherlands · Primary Hyperoxaluria
  2. Lumasiran Phase 3 · Alnylam Netherlands · Primary Hyperoxaluria Type 1
  3. Lumasiran Phase 2 · Alnylam Netherlands · Haemodialysis
  4. Lumasiran Phase 2 · Alnylam Netherlands · PH1
  5. Lumasiran Phase 2 · Alnylam Netherlands · Primary Hyperoxaluria Type 1 (PH1)
  6. Lumasiran Phase 2 · Alnylam Netherlands · Recurrent Calcium Oxalate Kidney Stone Disease

Related & competitor drugs

  1. agalsidase alfa Alimentary tract and metabolism (A16)
  2. alogliptin Alimentary tract and metabolism (A10)
  3. alogliptin benzoate Alimentary tract and metabolism (A10)
  4. aprepitant Alimentary tract and metabolism (A04)
  5. budesonide Alimentary tract and metabolism (A07)
  6. canagliflozin Alimentary tract and metabolism (A10)

Frequently asked questions

What is lumasiran?

lumasiran (OXLUMO) is a hydroxyacid oxidase 1 mrna rnai inhibitor. Associated with Lacuna Pharma Pty Ltd.

What is the brand name for lumasiran?

OXLUMO is a marketed brand name for lumasiran. Check FDA Drugs@FDA for the current US label holder and prescribing information.